Table 2 b Genotype and allele distributions in patients with Stanford type B aortic dissection and control subjects
SNPs | Genotypes and Alleles | Frequencies N (%) | OR(95%CI) | P | |
|---|---|---|---|---|---|
cases | controls | ||||
TGFBR1 rs1626340 | AA | 22(6.9) | 36(11.3) | 1.0 | |
AG | 70(22.0) | 67(21.1) | 2.91(0.97–8.73) | 0.06 | |
GG | 53(16.7) | 70(22.0) | 0.67(0.20–2.25) | 0.52 | |
AA + AG/GG | 123(38.7) | 137(43.1) | 1.59(0.59–4.29) | 0.36 | |
A | 114(17.9) | 139(21.9) | |||
G | 176(27.7) | 207(32.5) | |||
TGFBR2 rs4522809 | AA | 67(19.7) | 102(30.0) | 1.0 | |
AG | 71(20.9) | 80(23.5) | 1.34(0.56–3.22) | 0.51 | |
GG | 8(2.4) | 12(3.5) | 0.66(0.11–3.85) | 0.65 | |
AA + AG/GG | 138(40.6) | 182(53.5) | 1.75(0.32–9.58) | 0.52 | |
A | 205(30.1) | 284(41.8) | |||
G | 87(12.8) | 104(15.3) | |||
TGFB1 rs1800469 | AA | 35(10.9) | 49(15.2) | 1.0 | |
AG | 65(20.2) | 95(29.5) | 1.15(0.41–3.22) | 0.78 | |
GG | 29(9.0) | 49(15.2) | 0.33(0.08–1.34) | 0.12 | |
AA + AG/GG | 100(31.1) | 144(44.7) | 3.43(1.04–11.30) | 0.04 | |
A | 135(21.0) | 193(30.0) | |||
G | 123(19.1) | 193(30.0) | |||
TGFB2 rs900 | AA | 10(2.9) | 9(2.7) | 1.0 | |
AT | 64(18.9) | 81(23.9) | 0.67(0.13–3.45) | 0.62 | |
TT | 71(20.9) | 104(30.7) | 0.59(0.11–3.14) | 0.54 | |
AA + AT/TT | 74(21.8) | 90(26.5) | 1.16(0.52–2.60) | 0.70 | |
A | 84(12.4) | 99(14.6) | |||
T | 206(30.4) | 289(42.6) | |||