Table 2 a Genotype and allele distributions in patients with Stanford type B aortic dissection and control subjects
SNPs | Genotypes and Alleles | Frequencies N (%) | OR(95%CI) | P | ||
|---|---|---|---|---|---|---|
Cases(158) | Controls(197) | |||||
MLL3 rs10244604 | AA | 117(34.5) | 159(46.9) | 1.0 | ||
AG | 26(7.7) | 33(9.7) | 1.13(0.44–2.94) | 0.80 | ||
GG | 2(0.6) | 2(0.6) | 0.64(0.04–10.6) | 0.76 | ||
AA + AG/GG | 143(42.2) | 192(56.6) | 1.59(0.1–26.1) | 0.75 | ||
A | 260(38.3) | 351(51.8) | ||||
G | 30(4.4) | 37(5.5) | ||||
rs6963460 | AA | 92(28.0) | 128(39.0) | 1.0 | ||
AG | 40(12.2) | 52(15.9) | 1.11(0.4–2.7) | 0.83 | ||
GG | 5(1.5) | 11(3.4) | 1.07(0.17–6.73) | 0.94 | ||
AA + AG/GG | 132(40.2) | 180(54.9) | 0.96(0.16–5.89) | 0.97 | ||
A | 224(34.1) | 308(47.0) | ||||
G | 50(7.6) | 74(11.3) | ||||
rs1137721 | CC | 46(13.8) | 75(22.5) | 1.0 | ||
CT | 81(24.3) | 90(26.9) | 4.33(1.51–12.40) | < 0.01 | ||
TT | 15(4.5) | 27(8.1) | 2.19(0.45–10.65) | 0.33 | ||
CC + CT/TT | 127(38.0) | 165(49.4) | 1.18(0.30–4.63) | 0.81 | ||
C | 173(25.9) | 240(35.9) | ||||
T | 111(16.6) | 144(21.6) | ||||