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Table 3 Medication after one year

From: Contemporary in-hospital and long-term prognosis of patients with acute ST-elevation myocardial infarction depending on renal function: a retrospective analysis

 

No CKD

CKD Stage 1

CKD Stage 2

CKD Stage 3

CKD Stage 4

CKD Stage 5

CKD Stage 5D

p value

Oral anticoagulant, % (95%CI)

12.5

(12.3–12.7)

18.4

(16.3–20.6)

21.2

(20.2–22.1)

25.7

(25.0–26.3)

25.0

(23.5–26.5)

21.7

(18.9–24.6)

17.7

(14.8–20.8)

< 0.001

Platelet inhibitor, % (95%CI)

95.9

(95.8–96.0)

94.4

(93.6–94.7)

94.2

(93.6–94.7)

91.8

(91.4–92.3)

88.6

(87.5–89.7)

90.5

(88.3–92.3)

94.9

(92.8–96.4)

< 0.001

Oral anticoagulant and/or platelet inhibitor, % (95%CI)

96.6

(96.5–96.7)

95.1

(94.7–95.7)

95.2

(94.7–95.7)

92.7

(92.3–93.1)

88.7

(87.6–89.8)

89.6

(87.3–91.5)

92.1

(89.6–94.0)

< 0.001

Statin, % (95%CI)

93.7

(93.5–93.8)

90.0

(88.2–91.6)

90.7

(90.0–91.3)

85.1

(84.6–85.7)

78.2

(76.7–79.6)

77.6

(74.5–80.3)

75.2

(71.6–78.4)

< 0.001

Beta-blocker, % (95%CI)

93.2

(93.1–93.4)

93.3

(91.7–94.6)

93.6

(93.0–94.1)

92.3

(91.9–92.7)

90.4

(89.3–91.3)

90.1

(87.9–92.0)

90.9

(88.4–92.9)

< 0.001

ACE inhibitor or ARB, % (95%CI)

93.1

(93.0–93.3)

94.3

(92.8–95.5)

94.1

(93.6–94.7)

93.0

(92.6–93.4)

89.6

(88.5–90.6)

82.2

(79.4–84.7)

76.7

(73.1–79.9)

< 0.001

All four drug groups*, % (95%CI)

83.4

(83.2–83.7)

79.3

(76.9–81.5)

81.5

(80.6–82.4)

74.7

(74.0–75.4)

65.0

(63.3–66.7)

59.4

(55.9–62.7)

53.7

(49.7–57.6)

< 0.001

  1. *The four drug groups are composed of (1) oral anticoagulant/platelet inhibitor, (2) statin, (3) beta blocker, (4) ACE inhibitor/ARB
  2. ACE denotes angiotensin-converting-enzyme; ARB, angiotensin II receptor blocker; CKD, chronic kidney disease
  3. Cumulative incidence functions to address the rates for medication after discharge determined by Nelson-Aalen estimates, where death was considered as a competing risk event. The presented rates represent the estimated rates of patients with at least one prescription in a one-year period after discharge. Differences between CKD stages were tested via Gray’s test