Table 2 In-hospital treatment and outcome
Parameter | No CKD | CKD Stage 1 | CKD Stage 2 | CKD Stage 3 | CKD Stage 4 | CKD Stage 5 | CKD Stage 5D | p value |
|---|---|---|---|---|---|---|---|---|
Patients, n (%) | 137,682 (78.6) | 1480 (0.8) | 8347 (4.8) | 20,458 (11.7) | 4960 (2.8) | 1295 (0.7) | 965 (0.6) | |
Mean length of hospital stay, years (± SD) | 10.9 (± 13.2) | 12.4 (± 12.9) | 13.3 (± 14.9) | 15.2 (± 16.3) | 17.1 (± 20.6) | 25.1 (± 29.4) | 16.9 (± 24.1) | < 0.001 |
Mean costs, Euro (± SD) | 8902 (± 14,789) | 9556 (± 12,081) | 10,050 (± 15,794) | 11,126 (± 17,867) | 13,323 (± 25,111) | 25,029 (± 39,673) | 15,183 (± 26,186) | < 0.001 |
Coronary artery disease | < 0.001 | |||||||
One-vessel disease, n (%) | 39,760 (28.9) | 292 (19.7) | 1734 (20.8) | 3284 (16.1) | 689 (13.9) | 167 (12.9) | 135 (14.0) | |
Two-vessel disease, n (%) | 36,125 (26.2) | 353 (23.9) | 1997 (23.9) | 4511 (22.1) | 841 (17.0) | 247 (19.1) | 164 (17.0) | |
Three-vessel disease, n (%) | 45,005 (32.7) | 628 (42.4) | 3476 (41.6) | 8952 (43.8) | 2118 (42.7) | 587 (45.3) | 489 (50.7) | |
Unknown, n (%) | 16,792 (12.2) | 207 (14.0) | 1140 (13.7) | 3711 (18.1) | 1312 (26.5) | 294 (22.7) | 177 (18.3) | |
Coronary angiography, n (%) | 123,858 (90.0) | 1261 (85.2) | 7171 (85.9) | 16,530 (80.8) | 3508 (70.7) | 982 (75.8) | 741 (76.8) | < 0.001 |
Percutaneous coronary intervention, n (%) | 116,204 (84.4) | 1138 (76.9) | 6510 (78.0) | 14,886 (72.8) | 3076 (62.0) | 834 (64.4) | 632 (65.5) | < 0.001 |
Drug-eluting stent, n (%) | 83,064 (71.5) | 792 (69.6) | 4458 (68.5) | 9680 (65.0) | 1860 (60.5) | 519 (62.2) | 407 (64.4) | < 0.001 |
Bare-metal stent only, n (%) | 26,160 (22.5) | 256 (22.5) | 1560 (24.0) | 3963 (26.6) | 914 (29.7) | 230 (27.6) | 142 (22.5) | 0.004 |
Coronary artery bypass grafting, n (%) | 6164 (4.5) | 111 (7.5) | 512 (6.1) | 1137 (5.6) | 265 (5.3) | 124 (9.6) | 75 (7.8) | < 0.001 |
Intervention and/or thrombolysis, n (%) | 125,539 (91.2)) | 1271 (85.9) | 7260 (87.0) | 16,725 (81.8) | 3557 (71.7) | 996 (76.9) | 758 (78.6) | < 0.001 |
Intra-aortic balloon pump, n (%) | 3847 (2.8) | 59 (4.0) | 295 (3.5) | 810 (4.0) | 246 (5.0) | 112 (8.7) | 42 (4.4) | < 0.001 |
Extracorporeal membrane oxygenation, n (%) | 1280 (0.9) | 13 (0.9) | 66 (0.8) | 213 (1.0) | 76 (1.5) | 37 (2.9) | 18 (1.9) | < 0.001 |
Cardiogenic shock, n (%) | 17,224 (12.5) | 230 (15.5) | 1175 (14.1) | 3597 (17.6) | 1154 (23.3) | 359 (27.7) | 206 (21.4) | < 0.001 |
Impella and/or intra-aortic balloon pump and/or extracorporeal membrane oxygenation or shock, n (%) | 18,557 (13.5) | 252 (17.0) | 1285 (15.4) | 3895 (19.0) | 1231 (24.8) | 396 (30.6) | 229 (23.7) | < 0.001 |
GpIIb/IIIa-inhibitor, n (%) | 34,771 (25.3) | 318 (21.5) | 1778 (21.3) | 3889 (19.0) | 707 (14.3) | 196 (15.1) | 123 (12.8) | < 0.001 |
Ventilation | 23,872 (17.3) | 312 (21.1) | 1646 (19.7) | 4913 (24.0) | 1564 (31.5) | 553 (42.7) | 346 (35.9) | < 0.001 |
Stroke, n (%) | 1917 (1.4) | 33 (2.2) | 166 (2.0) | 534 (2.6) | 149 (3.0) | 53 (4.1) | 19 (2.0) | < 0.001 |
In-hospital resuscitation, n (%) | 13,940 (10.1) | 173 (11.7) | 823 (9.9) | 2521 (12.3) | 741 (14.9) | 256 (19.8) | 223 (23.1) | < 0.001 |
Blood transfusion, n (%) | 11,327 (8.2) | 193 (13.0) | 1024 (12.3) | 3364 (16.4) | 1198 (24.2) | 508 (39.2) | 253 (26.2) | < 0.001 |
Bleeding, n (%) | 9701 (7.0) | 107 (7.2) | 687 (8.2) | 1926 (9.4) | 521 (10.5) | 189 (14.6) | 89 (9.2) | < 0.001 |
Blood transfusion and/or bleeding, n (%) | 18,124 (13.2) | 260 (17.6) | 1454 (17.4) | 4412 (21.6) | 1405 (28.3) | 556 (42.9) | 282 (29.2) | < 0.001 |
Sepsis, n (%) | 2838 (2.1) | 46 (3.1) | 248 (3.0) | 746 (3.6) | 298 (6.0) | 140 (10.8) | 61 (6.3) | < 0.001 |
Renal replacement therapy, n (%) | 2943 (2.1) | 57 (3.9) | 266 (3.2) | 1032 (5.0) | 567 (11.4) | 674 (52.1) | 575 (59.6) | < 0.001 |
Acute renal failure, n (%) | 6808 (4.9) | 139 (9.4) | 729 (8.7) | 2971 (14.5) | 1,246 (25.1) | 392 (30.2) | 55 (5.7) | < 0.001 |
Acute renal failure and/or renal replacement therapy, n (%) | 7,379 (5.4) | 151 (10.2) | 795 (9.5) | 3,201 (15.6) | 1,398 (28.2) | 783 (60.5) | 586 (60.7) | < 0.001 |
In-hospital death, n (%) | 18,346 (13.3) | 272 (18.4) | 1,346 (16.1) | 4,580 (22.4) | 1,780 (35.9) | 482 (37.2) | 360 (37.3) | < 0.001 |
30-day mortality, n (%) | 18,813 (13.7) | 280 (18.9) | 1,414 (16.9) | 4,735 (23.1) | 1,817 (36.6) | 437 (33.8) | 359 (37.2) | < 0.001 |