Comparison of risk assessment strategies incorporating coronary artery calcium score with estimation of pretest probability to defer cardiovascular testing in patients with stable chest pain

Table 4 Reclassification table comparing CACS-CL to ESC strategy

	Risk groups by CACS-CL strategy		Total	Reclassification^a		NRI^b	p
	Low	High	Total	Up	Down	NRI^b	p
Risk groups by ESC strategy
Negative patients				2%	19%	19%	< 0.0001
Low	2107	67	2174
High	801	1309	2110
Total	2908	1376	4284
Positive patients^c				3%	1%
Low	121	32	153
High	13	839	852
Total	134	871	1005

CACS-CL strategy CACS-weighted clinical likelihood model-based risk assessment strategy, ESC strategy 2019 European Society of Cardiology guideline-determined risk assessment strategy, CCTA coronary computed tomographic angiography, CAD coronary artery disease, NRI net reclassification improvement
^aThe classification of patients by CACS-CL strategy was compared to that by CACS strategy
^bNRI = [P(Up|Positive)−P(Down|Positive)]−[P(Up|Negative)−P(Down|Negative)]
^cPositive patient was defined as an individual had at least one lesion with ≥ 50% diameter stenosis or any non-assessable segments because of severe calcification on CCTA

ISSN: 1471-2261