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Table 2 Discriminations of CACS-CL and ESC-PTP model

From: Comparison of risk assessment strategies incorporating coronary artery calcium score with estimation of pretest probability to defer cardiovascular testing in patients with stable chest pain

 

AUC

IDI

Statistic

95% CI

p

PTP

Statisticb

p

Positivea (%)

Negative (%)

ESC-PTP model

0.735

0.722 to 0.748

 < 0.0001

42%

19%

9%

 < 0.0001

CACS-CL model

0.838

0.827 to 0.848

45%

13%

  1. AUC Area under the receiver operating characteristic curve, IDI integrated discrimination improvement, CI confidence interval, CCTA coronary computed tomographic angiography, CACS-CL coronary artery calcium score–weighted clinical likelihood, PTP pretest probability, ESC 2019 European Society of Cardiology guideline
  2. aPositive patient was defined as an individual had at least one lesion with ≥ 50% diameter stenosis or any non-assessable segments because of severe calcification on CCTA
  3. bCompared to ESC-PTP model, the IDI of CACS-CL model = [P(CACS-CL|Positive)−P(ESC-PTP|Positive)]−[P(CACS-CL|Negative)−P(ESC-PTP|Negative)]