| AUC | IDI |
---|
Statistic | 95% CI | p | PTP | Statisticb | p |
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Positivea (%) | Negative (%) |
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ESC-PTP model | 0.735 | 0.722 to 0.748 |  < 0.0001 | 42% | 19% | 9% |  < 0.0001 |
CACS-CL model | 0.838 | 0.827 to 0.848 | 45% | 13% |
- AUC Area under the receiver operating characteristic curve, IDI integrated discrimination improvement, CI confidence interval, CCTA coronary computed tomographic angiography, CACS-CL coronary artery calcium score–weighted clinical likelihood, PTP pretest probability, ESC 2019 European Society of Cardiology guideline
- aPositive patient was defined as an individual had at least one lesion with ≥ 50% diameter stenosis or any non-assessable segments because of severe calcification on CCTA
- bCompared to ESC-PTP model, the IDI of CACS-CL model = [P(CACS-CL|Positive)−P(ESC-PTP|Positive)]−[P(CACS-CL|Negative)−P(ESC-PTP|Negative)]