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Table 1 Baseline demographic and clinical characteristics of study participants

From: Elevated circulating levels of gasdermin D are related to acute myocardial infarction and pyrogptosis

Characteristic

Control group (n = 50)

AMI with single vessel disease group (n = 40)

P value

AMI with multivessel disease group (n = 60)

P value

Age (years)

64.10 ± 9.88

59.90 ± 12.72

0.081

63.14 ± 12.36

0.108

Female

25 (50.0%)

10 (25.0%)

0.015**

41 (37.0%)

0.011**

Smoking

10 (20.0%)

22 (55.0%)

0.001**

40 (36.0%)

0.001**

Hypertension

30 (60.0%)

18 (45.0%)

0.160

64 (58.0%)

0.727

Hyperlipidemia

27 (54.0%)

23 (58.0%)

0.607

51 (46.0%)

0.283

Diabetes

6 (12.0%)

6 (15.0%)

0.068

24 (22.0%)

0.023*

GSDMD level

1.500 ± 0.51

2.320 ± 0.52

0.001**

2.991 ± 0.64

0.001**

LDL-C (mmol/L)

2.68 ± 1.02

3.21 ± 1.15

0.001**

2.92 ± 0.93

0.012**

HDL-C (mmol/L)

1.14 ± 0.32

1.09 ± 0.26

0.364

1.12 ± 0.27

0.347

CRP (mg/L)

3.77 ± 5.95

13.24 ± 15.43

0.001**

12.83 ± 19.35

0.001**

TC (mmol/L)

4.33 ± 1.23

5.25 ± 1.42

0.001**

4.66 ± 1.13

0.001**

TG (mmol/L)

1.60 ± 0.70

1.89 ± 2.10

0.368

1.48 ± 0.78

0.140

UA (μmol/L)

351.32 ± 86.21

363.03 ± 126.78

0.639

374.67 ± 128.95

0.083

WBC (× 109/L)

6.21 ± 1.78

9.03 ± 2.69

0.001**

7.51 ± 2.52

0.001**

RDW (%)

12.95 ± 0.61

13.20 ± 1.15

0.191

13.12 ± 0.79

0.044*

Thyroxine (nmol/L)

96.40 ± 17.72

96.06 ± 17.44

0.012*

106.83 ± 24.41

0.635

LAD (mm)

38.54 ± 4.60

38.60 ± 4.72

0.952

38.80 ± 4.30

0.565

LVEDD (mm)

48.24 ± 4.74

49.53 ± 4.87

0.021*

49.75 ± 5.31

0.006**

LVEF (%)

67.24 ± 6.85

51.68 ± 9.27

0.001**

56.88 ± 11.76

0.001**

  1. Data presented as mean ± standard deviation for variables
  2. LDL-C, low density lipoprotein-cholesterol; HDL-C, high density lipoprotein-cholesterol; CRP, C-reaction protein; TG, triglycerides; TC, total cholesterol; UA, uric acid; WBC, white blood count; RDW, red–cell distribution width; LAD, left atrial diameter; LVEDD, left ventricular end-diastolic dimension; LVEF, left ventricular ejection fraction
  3. *P < 0.05; ⁎⁎P < 0.01