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Table 4 Cox proportional hazard regression of time to long term mortality

From: Comparison of the red blood cell indices based on accuracy, sensitivity, and specificity to predict one-year mortality in heart failure patients

Variables

Long-term mortality

  

Univariate analysis

Multivariate analysis

 

HR (95% CI) 2

P 1

HR (95% CI) 2

P 1

Age

1.017 (0.997; 1.036)

0.090

1.013 (0.993; 1.034)

0.206

Men*

0.970 (0.573; 1.640)

0.908

1.138 (0.644; 2.011)

0.655

BMI

1.092 (1.017; 1.219)

0.015

1.098 (1.018; 1.186)

0.016

Ejection fraction

0.985 (0.966; 1.005)

0.145

0.988 (0.966; 1.011)

0.297

SBP

0.993 (0.983; 1.003)

0.176

0.996 (0.984; 1.007)

0.476

Etiology of HF*

 

0.297

 

0.438

Infection

1.976 (0.535; 7.299)

0.307

1.565 (0.413; 5.935)

0.510

Hypertensive

2.115 (0.529; 8.456)

0.290

1.728 (0.421; 7.088)

0.448

Cardiac arrhythmia

3.275 (0.989; 10.84)

0.052

2.562 (0.752; 8.722)

0.132

Valvular heart disease

3.109 (0.778; 12.43)

0.109

2.805 (6.679; 11.58)

0.154

Ischemic heart disease

1.819 (0.483; 6.856)

0.377

1.442 (0.366; 5.678)

0.601

Type HF(De novo)*

0.898 (0.509; 1.584)

0.710

1.056 (0.580; 1.925)

0.858

RBC count

0.782 (0.552; 1.108)

0.166

0.841 (0.335; 1.347)

0.712

Hemoglobin

0.878 (0.782; 0.986)

0.028

0.728 (0.553; 0.958)

0.024

Hematocrit

0.945 (0.905; 0.986)

0.010

0.875 (0.759; 1.009)

0.066

MCV

0.982 (0.953; 1.012)

0.230

1.007 (0.952; 1.066)

0.805

MCH

0.922 (0.855; 0.994)

0.033

0.998 (0.798; 1.119)

0.916

MCHC

0.761 (0.640; 0.905)

0.002

0.795 (0.641; 0.987)

0.037

RDW-CV

1.202 (1.101; 1.312)

p < 0.001

1.174 (1.046; 1.317)

0.006

  1. BMI Body mass index; SBP Systolic blood pressure; HF Heart failure; RBC Red blood cell; MCV Mean corpuscular volume; MCH Mean corpuscular hemoglobin; MCHC Mean corpuscular hemoglobin concentration; RDW Red blood cell distribution width.
  2. All statistically significant p values (p < 0.05) are in bold.
  3. 1 Statistical significance of hazard ratio.
  4. 2 Hazard ratio calculated by multivariate Cox proportional hazard regression for long-term mortality and its 95% confidence interval.
  5. * Women, dilated cardiomyopathy, and decompensated heart failure were considered the constant values for the sex, etiology, and type of heart failure, respectively.