Fig. 4

Circ_0004104 regulated the progression of HUVECs through targeting miR-942-5p. HUVECs were treated with Control, ox-LDL, ox-LDL + si-NC, ox-LDL + si-circ_0004104, ox-LDL + si-circ_0004104 + anti-miR-NC, or ox-LDL + si-circ_0004104 + anti-miR-942-5p. A qRT-PCR analysis of miR-942-5p in treated HUVECs. B–G Cell viability, apoptosis, tube formation, protein expression levels, and inflammatory factors in treated HUVECs were detected using MTT, flow cytometry, tube formation, western blot, and ELISA assays. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. All cellular experiments were independently repeated three times. One-way ANOVA was utilized to analyze the differences in (A, B, D, and E), while two-way ANOVA was utilized to assess the differences in (C, F, and G)