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Table 2 Adjusted CAC Volume and Density Among Those with DM or MetS

From: Coronary calcium density in relation to coronary heart disease and cardiovascular disease in adults with diabetes or metabolic syndrome: the Multi-ethnic Study of Atherosclerosis (MESA)

 

DM

(n = 668)

MetS

(n = 1122)

Neither DM/MetS

(n = 2028)

p value

CAC volume (95%CI)

Overall

79.46 (71.97–87.72)§

60.53 (55.46–66.08)‡

51.77 (48.01–55.82)

< 0.0001

Non-statin users

72.17 (64.44–80.81)§

56.58 (51.72–61.89)*

48.61 (45.16–52.32)

< 0.0001

Statin users

98.12 (80.60-119.44)§

69.32 (56.62–84.88)

57.24 (47.59–68.85)

< 0.0001

CAC density (95%CI)

Overall

2.54 (2.49–2.59)§

2.61 (2.57–2.65)‡

2.69 (2.65–2.72)

< 0.0001

Non-statin users

2.56 (2.51–2.62)§

2.62 (2.57–2.66)†

2.68 (2.65–2.72)

0.0001

Statin users

2.53 (2.44–2.62)§

2.65 (2.55–2.74)*

2.76 (2.67–2.84)

< 0.0001

  1. The mean CAC density (or ln(Volume)) was adjusted for ln(Volume) (or CAC density), age, sex, race/ethnicity, education, smoking status, statin use and hypertension medication
  2. P values were calculated from ANOVA test among three groups (last column) and from student t-tests comparing DM vs. neither DM/MetS and MetS versus neither DM/MetS (presented as symbols)
  3. CAC  Coronary artery calcium, DM  Diabetes mellitus, MetS  Metabolic syndrome
  4. *p < 0.05, †p < 0.01, ‡ p< 0.001, §p < 0.0001.