No plaque progression (n = 87) | Plaque progression (n = 161) | P value | |
---|---|---|---|
Male, n (%) | 58 (66.7) | 114 (70.8) | 0.500 |
Age, years | 65.71 ± 8.38 | 66.60 ± 9.77 | 0.476 |
Body mass index, kg/m2 | 24.63 ± 2.95 | 25.24 ± 3.31 | 0.154 |
Smoking, n (%) | 17 (19.5) | 65 (40.4) | 0.001 |
Hypertension, n (%) | 54 (62.1) | 128 (79.5) | 0.003 |
Dyslipidemia, n (%) | 14 (16.1) | 34 (21.1) | 0.339 |
Severity of CHD, n (%) | 0.217 | ||
1-Vessel | 25 (28.7) | 38 (23.6) | |
2-Vessel | 32 (36.8) | 49 (30.4) | |
3-Vessel | 30 (34.5) | 74 (46.0) | |
Systolic blood pressure, mm Hg | 138.74 ± 20.17 | 138.84 ± 19.85 | 0.967 |
Diastolic blood pressure, mm Hg | 74.91 ± 16.37 | 75.42 ± 10.75 | 0.766 |
Fasting blood glucose, mmol/L | 7.12 ± 1.80 | 7.04 ± 2.29 | 0.780 |
HbA1c, % | 7.27 ± 1.17 | 7.43 ± 1.45 | 0.367 |
Serum creatinine, μmol/L | 76.60 ± 19.79 | 84.14 ± 41.80 | 0.113 |
Serum BUN, mmol/L | 6.96 ± 3.04 | 6.67 ± 3.53 | 0.509 |
Serum uric acid, μmol/L | 334.90 ± 92.63 | 342.45 ± 91.04 | 0.536 |
eGFR, mL/min/1.73m2 | 84.64 ± 15.69 | 80.25 ± 18.56 | 0.062 |
Triglyceride, mmol/L | 1.69 ± 0.88 | 1.60 ± 0.98 | 0.465 |
Total cholesterol, mmol/L | 3.84 ± 1.17 | 3.96 ± 1.18 | 0.455 |
HDL cholesterol, mmol/L | 1.08 ± 0.28 | 1.06 ± 0.27 | 0.581 |
LDL cholesterol, mmol/L | 2.22 ± 0.89 | 2.37 ± 0.95 | 0.216 |
Apolipoprotein A, g/L | 1.25 ± 0.23 | 1.20 ± 0.23 | 0.095 |
Apolipoprotein B, g/L | 0.74 ± 0.22 | 0.79 ± 0.23 | 0.109 |
Lipoprotein (a), g/L | 0.22 ± 0.24 | 0.25 ± 0.26 | 0.458 |
CRP, mg/mL | 0.63 (0.28–2.43) | 1.14 (0.49–4.08) | 0.001 |
Medication, n (%) | |||
ACE inhibitors/ARBs | 55 (63.2) | 112 (69.6) | 0.309 |
β-blockers | 43 (49.4) | 96 (59.6) | 0.122 |
Statins | 80 (92.0) | 146 (90.7) | 0.985 |
Antiplatelet | 82 (94.3) | 154 (95.7) | 0.758 |
Metformin | 31 (35.6) | 54 (33.5) | 0.740 |
Insulin | 19 (21.8) | 36 (22.4) | 0.925 |
MPO level, ng/mL | 20.20 (19.20–27.00) | 33.30 (21.45–60.00) | < 0.001 |
MPO activity, mU/mL | 6.94 ± 5.20 | 10.37 ± 7.26 | < 0.001 |
Follow-up | |||
Duration, months | 12.18 ± 1.29 | 12.32 ± 1.24 | 0.428 |
Changes in MLD, mm | − 0.06 ± 0.09 | 0.67 ± 0.25 | < 0.001 |
Changes in stenosis diameter (%) | 0.88 ± 3.29 | − 22.70 ± 9.86 | < 0.001 |
Changes in CCSS | − 0.01 ± 0.08 | − 0.33 ± 0.15 | < 0.001 |