Table 2 Comparison of angiographic and computed tomography angiography characteristics at lesion-level
Calcified nodule (n = 12) | Non-nodular calcification (n = 116) | P value | |
|---|---|---|---|
Lesion location (%) | |||
LAD | 7 (58.33) | 63 (54.31) | 0.790 |
LCX | 3 (25.00) | 32 (27.59) | 1.000 |
RCA | 2 (16.67) | 21(18.10) | 1.000 |
Initial TIMI flow grade 0–1 (%) | 1 (8.33) | 21 (18.10) | 0.684 |
Moderate to heavy calcification on angiography (%) | 9 (75.00) | 47 (40.52) | 0.017 |
Type B2/C lesion (%) | 8 (66.67) | 68 (58.62) | 0.720 |
Plaque computed tomography angiography analysis | |||
Minimal lumen diameter (mm) | 0.45 (0.35, 2.70) | 0.95 (0.25, 2.74) | 0.089 |
Reference vessel diameter (mm) | 3.55 (3.23, 4.02) | 3.36 (2.97, 3.89) | 0.350 |
Diameter stenosis (%) | 79.00 (52.00, 76.00) | 63.00 (39.02, 60.00) | 0.007 |
Lesion length (mm) | 23.85 (13.83, 44.93) | 19.75 (13.50, 31.70) | 0.416 |
Positive remodeling (%) | 0 | 24 (20.69) | 0.121 |
Mean plaque burden (%) | 85.40 (77.85, 91.85) | 77.05 (65.63, 82.60) | 0.005 |
Total plaque volume (mm3) | 378.00 (150.00, 870.00) | 290.00 (146.50, 520.75) | 0.364 |
Lipid volume (mm3) | 66.55 (31.78, 102.78) | 57.40 (36.03, 92.25) | 0.915 |
Fiber volume (mm3) | 90.40 (39.70, 110.68) | 86.30 (48.23, 131.28) | 0.731 |
Calcium volume (mm3) | 227.55 (80.03, 626.60) | 151.30 (53.78, 308.83) | 0.236 |
Lipid percentage (%) | 14.65 (12.70, 17.85) | 19.75 (16.03, 25.40) | 0.010 |
Fiber percentage (%) | 17.90 (14.08, 27.13) | 25.65 (20.88, 37.55) | 0.011 |
Calcium percentage (%) | 64.20 (46.80, 72.35) | 54.35 (38.73, 62.50) | 0.055 |
Total plaque density (HU) | 398.00 (301.00, 452.75) | 283.50 (188.75, 352.75) | 0.008 |
Lipid density (HU) | -3.00 (-9.75, 6.50) | 0.00 (-6.00, 5.75) | 0.559 |
Fiber density (HU) | 99.50 (98.00, 101.00) | 98.00 (96.00, 100.00) | 0.066 |
Calcium density (HU) | 530.00 (437.75, 599.75) | 495.50 (389.50, 548.25) | 0.277 |