Skip to main content

Table 2 Allele frequencies by loci for ABCB1 and CES1 in the subjects

From: The impact of ABCB1 and CES1 polymorphisms on the safety of dabigatran in patients with non-valvular atrial fibrillation

Gene

SNP

Genotype

N(%)

Minor allele

MAF(%)

HWE,

p value

ABCB1

rs4148738

CC

18(16.1)

C

39.7

0.9

 

CT

53(47.3)

   
 

TT

41(36.6)

   
 

rs1045642

AA

18(16.1)

A

37.9

0.45

 

AG

49(43.8)

   
 

GG

45(40.2)

   

CES1

rs2244613

GG

43(38.4)

T

40.2

0.25

 

GT

48(42.8)

   
 

TT

21(18.8)

   
 

rs8192935

AA

65(58.0)

G

22.8

0.33

 

AG

43(38.4)

   
 

GG

4(3.6)

   
  1. Abbreviations: SNP, single nucleotide polymorphism; MAF, minor allele frequency; HWE, Hardy-Weinberg equilibrium