Univariate | Multivariate | ||||
---|---|---|---|---|---|
HR (95%CI) | p value | Adjusted HR (95%CI) | p value | ||
Total bilirubin, umol/L | 1.011 (0.997, 1.025) | 0.132 | |||
Direct bilirubin, umol/L | 1.109 (1.079, 1.140) | <0.001 | 1.069 (1.035, 1.103) | < 0.001 | |
Indirect bilirubin, umol/L | 0.996 (0.976, 1.015) | 0.650 | |||
Direct/indirect bilirubin ratio | 3.339 (2.352, 4.739) | <0.001 | 2.652 (1.577, 4.461) | <0.001 | |
Age, years | 1.088 (1.078, 1.099) | <0.001 | 1.056 (1.042, 1.070) | <0.001 | |
Male gender | 1.161 (0.967, 1.393) | 0.110 | |||
BMI, kg/m2 | 0.936 (0.911, 0.961) | <0.001 | 0.966 (0.938, 0.995) | 0.023 | |
SBP, mmHg | 1.009 (1.004, 1.014) | <0.001 | 1.007 (1.001, 1.013 ) | 0.027 | |
DBP, mmHg | 0.987 (0.979, 0.995) | 0.002 | 0.993 (0.982, 1.004) | 0.225 | |
Heart rate, bpm | 1.024 (1.019, 1.030) | <0.001 | 1.014 (1.007, 1.020) | <0.001 | |
Medical history | |||||
Current/ex-Smoker | 1.031 (0.864, 1.231) | 0.732 | |||
Hypertension | 1.391 (1.132, 1.710) | 0.002 | 1.047 (0.817, 1.342) | 0.716 | |
Diabetes | 1.412 (1.182, 1.686) | <0.001 | 0.878 (0.685, 1.125) | 0.304 | |
Dyslipidemia | 0.854 (0.714, 1.021) | 0.084 | |||
Previous Stroke | 2.170 (1.777, 2.649) | <0.001 | 1.427 (1.139, 1.788) | 0.002 | |
Previous MI | 1.970 (1.575, 2.464) | <0.001 | 1.215 (0.899, 1.641) | 0.206 | |
Past PCI | 1.380 (1.110, 1.716) | 0.004 | 1.199 (0.900, 1.596) | 0.215 | |
Past CABG | 2.153 (1.404, 3.301) | <0.001 | 1.389 (0.842, 2.291) | 0.199 | |
Medication on admission | |||||
Antiplatelet agent | 1.033 (0.863, 1.237) | 0.722 | |||
ACEI/ARB | 1.060 (0.882, 1.274) | 0.536 | |||
Beta-blocker | 0.783 (0.625, 0.980) | 0.033 | 0.865 (0.663, 1.128) | 0.284 | |
Statins | 0.699 (0.568, 0.862) | 0.001 | 0.789 (0.615, 1.013) | 0.063 | |
Laboratory data | |||||
WBC, 109/L | 1.047 (1.011, 1.084) | 0.010 | 1.038 (0.995, 1.083) | 0.085 | |
Hemoglobin, g/L | 0.988 (0.985, 0.991) | <0.001 | 0.995 (0.990, 1.000) | 0.032 | |
HsCRP, mg/L | 1.033 (1.026, 1.041) | <0.001 | |||
RBG at admission, mmol/L | 1.062 (1.041, 1.084) | <0.001 | |||
FPG, mmol/L | 1.104 (1.071, 1.139) | <0.001 | |||
HbA1c, % | 1.176 (1.111, 1.243) | <0.001 | 1.169 (1.085, 1.260) | <0.001 | |
Albumin, g/L | 0.858 (0.839, 0.877) | <0.001 | 0.970 (0.943, 0.998) | 0.034 | |
ALT, U/L | 0.988 (0.982, 0.995) | 0.001 | 0.990 (0.983, 0.998) | 0.009 | |
AST, U/L | 1.001 (1.001, 1.002) | 0.086 | |||
ALP, U/L | 1.008 (1.004, 1.011) | <0.001 | |||
GGT, U/L | 1.002 (1.000, 1.004) | 0.054 | |||
ChE, | 0.685 (0.647, 0.725) | <0.001 | |||
Creatinine, umol/L | 1.025 (1.021, 1.029) | <0.001 | |||
eGFR, ml/min/1.73m2 | 0.961 (0.957, 0.966) | <0.001 | 0.988 (0.981, 0.994) | <0.001 | |
TC, mmol/L | 0.910 (0.833, 0.994) | 0.037 | 0.976 (0.870, 1.094) | 0.674 | |
TGs, mmol/L | 0.720 (0.639, 0.811) | <0.001 | 0.924 (0.813, 1.050) | 0.224 | |
LDLC, mmol/L | 0.943 (0.837, 1.063) | 0.337 | |||
HDLC, mmol/L | 0.783 (0.558, 1.098) | 0.156 | |||
Echocardiography | |||||
LVEF | 0.005 (0.003, 0.011) | <0.001 | 0.034 (0.013, 0.091) | <0.001 | |
Angiography findings | |||||
LM/three-vessel | 2.936 (2.284, 3.774) | <0.001 | 1.666 (1.248, 2.224) | 0.001 | |
Proximal LAD | 1.411 (1.172, 1.700) | <0.001 | 1.026 (0.832, 1.265) | 0.813 | |
PCI/CABG | 1.049 (0.876, 1.258) | 0.601 | |||
Medication during hospitalization | |||||
Antiplatelet agent | 0.634 (0.405, 0.992) | 0.046 | 0.684 (0.394, 1.188) | 0.178 | |
ACEI/ARB | 1.328 (1.105, 1.597) | 0.003 | 0.995 (0.794, 1.245) | 0.962 | |
Beta-blocker | 1.009 (0.831, 1.225) | 0.931 | |||
Statins | 0.714 (0.537, 0.949) | 0.020 | 0.837 (0.581, 1.205) | 0.339 |