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Table 2 Mean and SD of anthropometric body composition, blood parameters and blood pressure across to GRS.

From: The relationship of genetic risk score with cardiometabolic risk factors: a cross-sectional study

Variables†

GRS

 

Low risk (164)

Moderate risk (97)

High risk (130)

P-value

P-value b

> 3

3

3 <

Age (years)

36.66 ± 9.51

37.20 ± 8.85

36.27 ± 8.83

0.72

0.76

Body weight (Kg)

79.88 ± 10.29

80.50 ± 11.56

81.73 ± 12.56

0.38

0.69a

BMI (Kg/m2)

30.30 ± 3.60

31.16 ± 3.79

31.63 ± 4.07

0.01

0.04

Body composition

 

WC (cm)

98.05 ± 9.01

99.41 ± 9.48

100.15 ± 10.16

0.18

0.25 a

WHR (ratio)

0.93 ± 0.05

0.93 ± 0.04

1.55 ± 7.51

0.43

0.50 a

BFM (kg)

32.98 ± 7.22

34.75 ± 7.96

35.21 ± 8.70

0.05

0.05 a

BF (%)

41.18 ± 5.10

42.61 ± 4.95

42.46 ± 5.67

0.05

0.03 a

BMR (kcal)

1377.30 ± 115.06

1376.30 ± 164.83

1371.17 ± 123.62

0.91

0.58 a

BMC (g)

2.68 ± 0.33

2.64 ± 0.35

2.63 ± 0.35

0.37

0.21 a

SMM (kg)

25.58 ± 3.18

25.26 ± 3.45

25.53 ± 3.52

0.75

0.74 a

Blood pressure

 

SBP (mmHg)

110.71 ± 11.90

111.44 ± 15.30

111.95 ± 13.91

0.79

0.81

DBP (mmHg)

77.42 ± 9.63

77.81 ± 10.11

77.82 ± 9.17

0.94

0.72

Blood parameters

 

FBS (mg/Dl)

87.21 ± 9.14

85.71 ± 7.68

88.36 ± 11.30

0.26

0.64

Total cholesterol (g/dl)

186.93 ± 34.22

185.36 ± 38.54

179.62 ± 34.19

0.35

0.32

TG (mg/dl)

122.21 ± 67.58

109.23 ± 51.23

127.14 ± 79.19

0.28

0.29

HDL (mg/dl)

46.92 ± 9.86

48.41 ± 12.32

44.60 ± 10.01

0.08

0.18

LDL (mg/dl)

95.92 ± 22.08

97.91 ± 25.29

90.78 ± 24.33

0.15

0.19

hs-CRP (mg/L)

4.63 ± 3.97

4.70 ± 4.18

5.78 ± 5.17

0.06

0.05

HOMA index

3.38 ± 1.16

3.12 ± 1.12

3.48 ± 1.45

0.22

0.38

Insulin (mIU/ ml)

1.20 ± 0.23

1.21 ± 0.22

1.23 ± 0.24

0.63

0.64

MCP-1 (ng/ml)

47.86 ± 90.28

49.30 ± 85.48

54.51 ± 101.29

0.89

0.69

Galectin3 (ng/ml)

3.44 ± 6.91

5.53 ± 7.90

3.99 ± 7.51

0.63

0.48

PAI-1 (ng/ml)

17.10 ± 35.99

11.55 ± 18.08

18.41 ± 29.51

0.49

0.54

  1. SD: Standard deviation; GRS: Genetic risk score; BMI: Body mass index; WC: waist circumference; WHR: waist height ratio; BFM: body fat mass; BF: body fat; BMR: Basal metabolic rate; BMC: bone mineral content; SMM: skeletal muscle mass; SBP: Systolic blood pressure; DBP: Diastolic Blood Pressure; FBS: fasting blood sugar; TG: Triglyceride; LDL: Low density lipoprotein; HDL: High density lipoprotein; hs-CRP: High-sensitivity C-reactive protein; MCP-1: monocyte chemoattractant protein; PAI-1: Plasminogen Activator Inhibitor 1
  2. † Calculated by analysis of variance (ANOVA)
  3. a BMI considered as collinear and this variable adjusted for age, physical activity, and smoking
  4. b Adjusted for age, BMI, physical activity