Skip to main content

Table 3 ORs for wide QRS complex and prolonged QTc interval according to fibroblast growth factor 21 tertiles (95% CI)

From: Fibroblast growth factor 21 is associated with widening QRS complex and prolonged corrected QT interval in patients with stable angina

Factor

Low FGF21

 ≤ 28.5 pg/mL

Medium FGF21

 = 28.6–65.8 pg/mL

High FGF21

 > 65.8 pg/mL

P for trend

Number

108

106

107

 

Wide QRS complex

 Model 1

1.00

1.60 (0.63–4.24)

5.57 (2.54–13.61)

 < 0.0001

 Model 2

1.00

1.54 (0.61–4.10)

5.16 (2.32–12.74)

 < 0.0001

 Model 3

1.00

1.54 (0.59–4.19)

4.92 (2.18–12.27)

 < 0.0001

 Model 4

1.00

1.39 (0.51–3.90)

4.41 (1.84–11.59)

0.001

Prolonged QTc interval

 Model 1

1.00

1.12 (0.62–2.04)

2.37 (1.35–4.21)

0.003

 Model 2

1.00

1.09 (0.60–1.98)

2.08 (1.17–3.74)

0.013

 Model 3

1.00

1.05 (0.57–1.95)

2.14 (1.19–3.89)

0.011

 Model 4

1.00

1.02 (0.53–1.78)

1.93 (1.04–3.60)

0.037

  1. Model 1 unadjusted model, Model 2 adjusted for age and sex, Model 3 additionally adjusted for body mass index, total-cholesterol, potassium, and smoking, Model 4 additionally adjusted for diabetes mellitus, hypertension, chronic kidney disease, statins medication. FGF fibroblast growth factor