Fig. 1
a, b Nasal granulomatous. Presence in nasal biopsies of an inflammatory granulation tissue, formed of histiocyte lymphocytes, of a few rare plasmacytes and especially many granulocytes. There is no caseous necrosis. Presence of a small granuloma with giant cells embedded in the inflammatory reaction (arrow) (H.E. x 20 in a, x 40 in b). c Skin bleb. Subepidermal detachment with formation of a space partially filled with inflammatory and fibrinoid material (H.E. x 20). d Skin granulomatous. Histologic section of skin biopsy showing signs of vasculitis (arrow) with parietal necrosis fibrinoid (H.E. x 20)