Cause domain, total = 327 | Frequency (%) |
---|---|
C1: Drug selection causes | 109 (33.33) |
 New indication for drug treatment | 67 (61.47) |
 Inappropriate drug according to guidelines | 19 (17.43) |
 Contra-indicated | 7 (6.42) |
 No indication for drug | 6 (5.50) |
 Inappropriate combination of drugs, drugs, and foods | 6 (5.50) |
 Inappropriate duplication of therapeutic agents | 4 (3.68) |
C2: Drug form causes | 33 (10.09) |
 Inappropriate drug form | 33 (100) |
C3: Dose selection causes | 67 (20.49) |
 Dosage regimen not too frequent | 32 (47.76) |
 Drug dose too high | 17 (25.37) |
 Drug dose too low | 10 (14.93) |
 Dosage regimen too frequent | 8 (11.94) |
C4: treatment duration causes | 1 (0.31) |
 Duration of treatment too long | 1 (100) |
C5: Dispensing causes | 7 (2.14) |
 Prescribed drug not available | 5 (71.43) |
 Necessary information not available | 2 (28.57) |
C6: Drug use process causes | 17 (5.20) |
 Drug under administered | 11 (64.70) |
 Inappropriate timing of administration | 3 (17.65) |
 Drug not administered at all | 3 (17.65) |
C7: Patient-related causes | 63 (19.27) |
 Patient unable to understand instructions | 33 (52.38) |
 A patient takes less drug than prescribed | 17 (26.98) |
 A patient takes more drugs than prescribed | 7 (11.11) |
 Inappropriate timing or dosing intervals | 5 (7.94) |
 A patient uses unnecessary drug | 1 (1.59) |
C8: Other causes | 30 (9.17) |
 Not safe or drug-drug interaction | 17 (56.67) |
 No or inappropriate outcome monitoring | 13 (43.33) |