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Fig. 4 | BMC Cardiovascular Disorders

Fig. 4

From: The synergistic mechanism of fibroblast growth factor 18 and integrin β1 in rat abdominal aortic aneurysm repair

Fig. 4

a Survival curves of rats in different groups; mortality of the Sham group was 0 within 4 weeks after surgery; three rats in the experimental groups died within 2 weeks after surgery, and the overall mortality of the experimental groups within 4 weeks after surgery was 6.25% (3/48). b The AAA incidence rate of rats in different groups: forty rats developed AAA: 10 in the AAA group, 10 in the AAA + FGF18 group, 11 in the AAA + LV-Itgβ1 group, and nine in the AAA + FGF18 + LV-Itgβ1 group; there was no significant difference in the morbidity and mortality between the experimental groups (p > 0.05). (c, d) The abdominal aorta dilation rate of different groups at 0–4 weeks after the operation. There was no significant difference in the abdominal aorta dilation rate between groups 2 weeks after the operation (p > 0.05); four weeks after the operation, the abdominal aorta dilation rate of the AAA + FGF18 + LV-Itgβ1 group was the lowest, whereas that of the AAA group was the highest; there was a significant difference between them (p < 0.01); **p < 0.01

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