Table 1 Baseline clinical characteristics of patients based on in-hospital mortality
From: Impact of lactate dehydrogenase on prognosis of patients undergoing cardiac surgery
Variables | MIMIC III | MIMIC IV | ||||
|---|---|---|---|---|---|---|
Survivors | Non-survivors | P | Survivors | Non-survivors | P | |
N = 2247 | N = 78 | N = 1352 | N = 35 | |||
Age, years | 69.2 (60.4–77.5) | 73.6 (65.0–78.9) | 0.023 | 69.0 (61.0–77.0) | 75.0 (58.5–82.0) | 0.104 |
Male, n (%) | 1516 (67.5) | 50 (64.1) | 0.617 | 945 (69.9) | 22 (62.9) | 0.479 |
Marital, n (%) | 0.098 | 0.052 | ||||
Married | 1349 (60.0) | 46 (59.0) | 782 (57.8) | 16 (45.7) | ||
Un-married | 810 (36.0) | 25 (32.1) | 500 (37.0) | 14 (40.0) | ||
Unknown | 88 (3.9) | 7 (9.0) | 70 (5.2) | 5 (14.3) | ||
Ethnicity, n (%) | 0.043 | 0.193 | ||||
White | 1603 (71.3) | 48 (61.5) | 941 (69.6) | 22 (62.9) | ||
Non-white | 234 (10.4) | 7 (9.0) | 185 (13.7) | 3 (8.6) | ||
Unknown | 410 (18.2) | 23 (29.5) | 226 (16.7) | 10 (28.6) | ||
BMI, kg/m2 | 27.6 (24.6–31.6) | 28.4 (25.0–32.8) | 0.218 | 28.8 (25.5–33.0) | 30.8 (25.3–35.9) | 0.152 |
SBP, mmHg | 115 (102–128) | 108 (96–126) | 0.018 | 122 (104–140) | 133 (98–153) | 0.720 |
DBP, mmHg | 59 (52–67) | 56 (48–62) | 0.009 | 65 (54–90) | 66 (52–90) | 0.979 |
Heart rate, bpm | 84 (77–90) | 88 (80–99) | < 0.001 | 80 (69–90) | 80 (60–103) | 0.706 |
Hypertension, n (%) | 1330 (59.2) | 30 (38.5) | < 0.001 | 803 (59.4) | 13 (37.1) | 0.014 |
Diabetes, n (%) | 753 (33.5) | 25 (32.1) | 0.883 | 479 (35.4) | 11 (31.4) | 0.757 |
CHD, n (%) | 1749 (77.8) | 50 (64.1) | 0.007 | 1059 (78.3) | 25 (71.4) | 0.442 |
Valve disease, n (%) | 1109 (49.4) | 45 (57.7) | 0.183 | 680 (50.3) | 22 (62.9) | 0.195 |
Heart failure, n (%) | 841 (37.4) | 51 (65.4) | < 0.001 | 463 (34.2) | 26 (74.3) | < 0.001 |
COPD, n (%) | 27 (1.2) | 2 (2.6) | 0.254 | 12 (0.9) | 0 (0.0) | 1.000 |
CKD, n (%) | 282 (12.6) | 15 (19.2) | 0.118 | 236 (17.5) | 16 (45.7) | < 0.001 |
LDH, u/l | 228 (184, 320) | 436 (278–966) | < 0.001 | 206 (171–256) | 299 (231–458) | < 0.001 |
WBC, k/ul | 8.6 (6.8–11.6) | 9.7 (7.3–13.3) | 0.088 | 7.8 (6.4–9.7) | 9.5 (7.3–13.1) | 0.006 |
PLT, k/u | 206 (161–257) | 205 (148–257) | 0.477 | 211 (172–262) | 231 (176–293) | 0.243 |
BUN, mg/dl | 19 (15–26) | 27 (18–42) | < 0.001 | 19 (15–26) | 29 (19–43) | < 0.001 |
SCr, mg/dl | 1.0 (0.8–1.3) | 1.3 (1.0–1.8) | < 0.001 | 1.0 (0.9–1.3) | 1.4 (1.1–1.9) | < 0.001 |
Sodium, mEq/l | 139 (137–141) | 138 (136–140) | 0.002 | 139 (137–141) | 138 (135–140) | 0.013 |
Potassium, mEq/l | 4.1 (3.9–4.5) | 4.2 (3.9–4.9) | 0.059 | 4.1 (3.9–4.4) | 4.2 (3.9–4.8) | 0.052 |
Glucose, mg/dl | 119 (101–151) | 124 (105–177) | 0.092 | 116 (99–152) | 120 (105–155) | 0.234 |
SAPS II | 36 (30–44) | 46 (36–56) | < 0.001 | 36 (29–43) | 46 (37–52) | < 0.001 |
SOFA score | 5 (3–7) | 8 (5–10) | < 0.001 | 2 (1–4) | 3 (1–4) | 0.397 |