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Table 1 Baseline clinical characteristics of patients based on in-hospital mortality

From: Impact of lactate dehydrogenase on prognosis of patients undergoing cardiac surgery

Variables MIMIC III MIMIC IV
Survivors Non-survivors P Survivors Non-survivors P
N = 2247 N = 78 N = 1352 N = 35
Age, years 69.2 (60.4–77.5) 73.6 (65.0–78.9) 0.023 69.0 (61.0–77.0) 75.0 (58.5–82.0) 0.104
Male, n (%) 1516 (67.5) 50 (64.1) 0.617 945 (69.9) 22 (62.9) 0.479
Marital, n (%)    0.098    0.052
Married 1349 (60.0) 46 (59.0)   782 (57.8) 16 (45.7)  
Un-married 810 (36.0) 25 (32.1)   500 (37.0) 14 (40.0)  
Unknown 88 (3.9) 7 (9.0)   70 (5.2) 5 (14.3)  
Ethnicity, n (%)    0.043    0.193
White 1603 (71.3) 48 (61.5)   941 (69.6) 22 (62.9)  
Non-white 234 (10.4) 7 (9.0)   185 (13.7) 3 (8.6)  
Unknown 410 (18.2) 23 (29.5)   226 (16.7) 10 (28.6)  
BMI, kg/m2 27.6 (24.6–31.6) 28.4 (25.0–32.8) 0.218 28.8 (25.5–33.0) 30.8 (25.3–35.9) 0.152
SBP, mmHg 115 (102–128) 108 (96–126) 0.018 122 (104–140) 133 (98–153) 0.720
DBP, mmHg 59 (52–67) 56 (48–62) 0.009 65 (54–90) 66 (52–90) 0.979
Heart rate, bpm 84 (77–90) 88 (80–99) < 0.001 80 (69–90) 80 (60–103) 0.706
Hypertension, n (%) 1330 (59.2) 30 (38.5) < 0.001 803 (59.4) 13 (37.1) 0.014
Diabetes, n (%) 753 (33.5) 25 (32.1) 0.883 479 (35.4) 11 (31.4) 0.757
CHD, n (%) 1749 (77.8) 50 (64.1) 0.007 1059 (78.3) 25 (71.4) 0.442
Valve disease, n (%) 1109 (49.4) 45 (57.7) 0.183 680 (50.3) 22 (62.9) 0.195
Heart failure, n (%) 841 (37.4) 51 (65.4) < 0.001 463 (34.2) 26 (74.3) < 0.001
COPD, n (%) 27 (1.2) 2 (2.6) 0.254 12 (0.9) 0 (0.0) 1.000
CKD, n (%) 282 (12.6) 15 (19.2) 0.118 236 (17.5) 16 (45.7) < 0.001
LDH, u/l 228 (184, 320) 436 (278–966) < 0.001 206 (171–256) 299 (231–458) < 0.001
WBC, k/ul 8.6 (6.8–11.6) 9.7 (7.3–13.3) 0.088 7.8 (6.4–9.7) 9.5 (7.3–13.1) 0.006
PLT, k/u 206 (161–257) 205 (148–257) 0.477 211 (172–262) 231 (176–293) 0.243
BUN, mg/dl 19 (15–26) 27 (18–42) < 0.001 19 (15–26) 29 (19–43) < 0.001
SCr, mg/dl 1.0 (0.8–1.3) 1.3 (1.0–1.8) < 0.001 1.0 (0.9–1.3) 1.4 (1.1–1.9) < 0.001
Sodium, mEq/l 139 (137–141) 138 (136–140) 0.002 139 (137–141) 138 (135–140) 0.013
Potassium, mEq/l 4.1 (3.9–4.5) 4.2 (3.9–4.9) 0.059 4.1 (3.9–4.4) 4.2 (3.9–4.8) 0.052
Glucose, mg/dl 119 (101–151) 124 (105–177) 0.092 116 (99–152) 120 (105–155) 0.234
SAPS II 36 (30–44) 46 (36–56) < 0.001 36 (29–43) 46 (37–52) < 0.001
SOFA score 5 (3–7) 8 (5–10) < 0.001 2 (1–4) 3 (1–4) 0.397
  1. MIMIC Medical Information Mart for Intensive Care, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, CHD coronary heart disease, COPD chronic obstructive pulmonary disease, CKD chronic kidney disease, LDH lactate dehydrogenase, WBC white blood cell count, PLT platelets, BUN blood urea nitrogen, SCr serum creatine, SAPS simplified acute physiology score, SOFA sequential organ failure assessment