Variables | The effective group (n = 66) | The non-effective group (n = 26) | χ2 | P |
---|---|---|---|---|
Sex (male/female) (n) | 31/35 | 14/12 | 0.353 | 0.552 |
Age (years) | 59.28 ± 10.65 | 59.67 ± 10.42 | − 0.159 | 0.874 |
BMI (kg/m2) | 23.43 ± 4.48 | 23.13 ± 4.93 | 0.375 | 0.709 |
NYHA cardiac function class (%) | ||||
II | 17 (25.76%) | 6 (23.08%) | 0.132 | 0.936 |
III | 19 (28.79%) | 7 (26.92%) | ||
IV | 30 (45.46%) | 13 (50.00%) | ||
Comorbidities (%) | ||||
Obesity | 6 (9.09%) | 4 (15.38%) | 0.763 | 0.383 |
COPD history | 7 (10.61%) | 2 (7.69%) | 0.179 | 0.672 |
Hyperlipidemia | 11 (16.67%) | 9 (34.62%) | 3.532 | 0.060 |
Diabetes | 14 (21.21%) | 5 (19.23%) | 0.045 | 0.833 |
Hypertension | 3(4.55%) | 8 (30.77%) | 12.185 | < 0.001 |
Drinking (n) | 12 (18.19%) | 5 (19.23%) | 0.014 | 0.907 |
Smoking (n) | 15 (22.73%) | 7 (26.92%) | 0.180 | 0.671 |
CHD (n) | 3 (4.55%) | 13 (50%) | 26.824 | < 0.001 |
Atrial fibrillation (n) | 4 (6.06%) | 2 (7.69%) | 0.081 | 0.775 |
Cerebrovascular disease (n) | 9 (13.64%) | 4 (15.38%) | 0.047 | 0.828 |
Valvular heart disease (n) | 3 (4.55%) | 14 (53.85%) | 8.169 | 0.004 |
Routine inspection indicators | ||||
BNP before treatment (ng/L) | 441.29 ± 78.93 | 440.78 ± 79.38 | 0.028 | 0.978 |
BNP after treatment (ng/L) | 303.29 ± 71.29 | 337.92 ± 76.28 | − 1.701 | 0.092 |
NT-pro-BNP before treatment (ng/L) | 1461.89 ± 432.09 | 1459.87 ± 442.97 | 0.021 | 0.984 |
NT-pro-BNP after treatment (ng/L) | 518.75 ± 127.98 | 571.76 ± 136.93 | − 1.754 | 0.083 |
CTn-I before treatment (ng/L) | 245.98 ± 47.98 | 253.09 ± 49.82 | − 0.633 | 0.528 |
CTn-I after treatment (ng/L) | 193.98 ± 43.29 | 207.92 ± 47.93 | − 1.349 | 0.181 |
Serum iron (pg/dI) | 19.08 ± 3.29 | 18.28 ± 3.28 | 1.051 | 0.296 |
Serum sodium (mmol/L) | 134.78 ± 30.92 | 133.87 ± 32.56 | 0.125 | 0.903 |
Serum potassium (mmol/L) | 4.21 ± 0.76 | 4.19 ± 0.72 | 0.115 | 0.909 |
Blood glucose (mmol/L) | 5.01 ± 1.05 | 5.13 ± 1.09 | − 0.488 | 0.627 |
Glycated hemoglobin (%) | 5.37 ± 1.02 | 5.43 ± 1.05 | − 0.207 | 0.837 |
Blood urea nitrogen (mmol/L) | 6.03 ± 1.73 | 5.89 ± 1.83 | 0.335 | 0.739 |
Serum creatinine (μmol/L) | 93.29 ± 17.28 | 91.38 ± 16.53 | 0.493 | 0.624 |
eGFR (mL/min/1.73 m2) | 76.93 ± 12.38 | 74.73 ± 13.29 | 0.752 | 0.454 |
Echocardiography before treatment | ||||
LVEDd (mm) | 68.73 ± 7.09 | 69.21 ± 7.46 | − 0.288 | 0.774 |
LVIDs (mm) | 43.87 ± 6.87 | 44.91 ± 6.54 | − 0.662 | 0.502 |
LVEF (%) | 35.58 ± 5.91 | 34.98 ± 5.03 | 0.456 | 0.649 |
LVPWT (mm) | 14.23 ± 3.11 | 14.45 ± 3.18 | − 0.304 | 0.762 |
LVST (mm) | 14.87 ± 3.21 | 14.94 ± 3.42 | − 0.092 | 0.927 |
RA (mm) | 62.19 ± 12.87 | 62.79 ± 13.17 | − 0.198 | 0.842 |
RVD (mm) | 21.76 ± 4.98 | 21.85 ± 5.65 | − 0.075 | 0.944 |
Echocardiography after treatment | ||||
LVIDd | 49.87 ± 13.26 | 50.32 ± 13.18 | − 0.147 | 0.883 |
LVIDs (mm) | 39.65 ± 6.59 | 40.98 ± 6.75 | − 0.866 | 0.389 |
LVEF (%) | 47.93 ± 5.37 | 46.09 ± 5.48 | 1.404 | 0.640 |
LVPWT (mm) | 10.37 ± 2.78 | 11.09 ± 2.87 | − 1.108 | 0.271 |
LVST (mm) | 10.32 ± 3.01 | 10.89 ± 2.98 | − 0.819 | 0.414 |
RA (mm) | 49.38 ± 10.28 | 50.38 ± 10.03 | − 0.423 | 0.673 |
RVD (mm) | 16.03 ± 3.45 | 16.34 ± 3.56 | − 0.385 | 0.701 |