Skip to main content

Table 1 Characteristics of patients

From: Prediction of microvascular obstruction by coronary artery angiography score after acute ST-segment elevation myocardial infarction: a single-center retrospective observational study

Parameters Total population (n = 122) Non-MVO group (n = 71) MVO group (n = 51) p-value
Age (years) 60.6 ± 12.8 61.1 ± 14.1 59.8 ± 10.9 0.593
Male, n (%) 88 (72.1) 49 (69.0) 39 (76.5) 0.365
Heart rate (bpm) 79.8 ± 13.7 76.8 ± 12.9 82.9 ± 18.5 0.154
Systolic blood pressure (mmHg) 133.5 ± 20.7 133.0 ± 23.9 134.2 ± 15.5 0.733
Diastolic blood pressure (mmHg) 81.6 ± 14.1 80.6 ± 14.7 83.0 ± 13.2 0.345
Hypertension, n (%) 58 (47.5) 36 (50.7) 22 (43.1) 0.409
Diabetes, n (%) 32 (26.2) 17 (23.9) 15 (29.4) 0.498
Current Smoker, n (%) 27 (22.1) 13 (18.3) 14 (27.5) 0.230
Dyslipidemia, n (%) 16 (13.1) 10 (14.1) 6 (11.8) 0.708
GRACE score, n (%) 141.8 ± 29.0 133.2 ± 23.9 140.1 ± 31.2 0.188
Peak Troponin I (ng/ml) 23.7 (13.7 to 30.0) 15.8 (9.8 to 28.6) 30.0 (23.7 to 30.0)  < 0.001
Peak CK (U/L) 2748.5 (1432.5 to 3817.5) 1925.5 (1138.5 to 3053.0) 3505.0 (2708.5 to 6920.3)  < 0.001
Peak CK-MB (U/L) 270.0 (202.0 to 404.0) 211.0 (163.0 to 276.0) 346.0 (274.0 to 473.0)  < 0.001
PRO-BNP (pg/mL) 815.0 (432.5 to 1996.5) 683.5 (427.8 to 933.0) 987.0 (515.8 to 3205.3) 0.026
CRP (mg/L) 6.9 (3.2 to 17.1) 4.8 (3.0 to 13.5) 9.9 (4.2 to 25.9) 0.008
Serum creatinine (umol/L) 58.6 (49.9 to 75.6) 58.4 (48.7 to 72.0) 58.9 (52.0 to 79.8) 0.144
Serum uric acid (umol/L) 301.2 (242.2 to 383.1) 291.6 (236.1 to 362.6) 307.8 (244.9 to 405.5) 0.234
Albumin (g/L) 37.3 ± 4.3 37.1 ± 4.4 37.6 ± 4.0 0.592
Plasma fibrinogen (g/L) 2.6 ± 1.0 2.6 ± 1.0 2.6 ± 0.9 0.882
D-Dimer (ng/ml) 89.7 (67.4 to 154.5) 84.7 (67.5 to 125.0) 99.0 (67.1 to 187.0) 0.075
Neutrophil (× 109/L) 7.9 (6.3 to 10.3) 7.9 (6.1 to 9.8) 8.5 (6.3 to 10.7) 0.165
Lymphocyte (× 109/L) 1.3 (0.9 to 1.6) 1.2 (0.9 to 1.6) 1.3 (1.0 to 1.5) 0.682
Total cholesterol (mmol/L) 4.1 (3.6 to 4.8) 4.2 (3.6 to 4.8) 3.9 (3.5 to 4.9) 0.267
Triglyceride (mmol/L) 1.2 (0.8 to 1.6) 1.1 (0.8 to 1.6) 1.4 (0.9 to 1.7) 0.075
LDL-C (mmol/L) 2.5 ± 0.6 2.5 ± 0.7 2.5 ± 0.5 0.458
HDL-C (mmol/L) 1.2 (1.0 to 1.6) 1.2 (1.0 to 1.6) 1.2 (1.0 to 1.5) 0.769
Heart failure Killip class, n (%)
I 91 (74.6) 55 (77.5) 36 (70.6) 0.389
 ≥ II 31 (15.4) 16 (12.5) 15 (29.4)  
Time from symptom onset to PCI (h) 6.2 (4.5 to 9.3) 6.0 (5.0 to 9.0) 6.2 (4.0 to 11.3) 0.545
Culprit artery, n (%)
LAD 66 (54.1) 28 (39.4) 38 (74.5)  < 0.001
LCX 9 (7.4) 6 (8.5) 3 (5.9) 0.592
RCA 47 (38.5) 37 (52.1) 10 (19.6)  < 0.001
Number of diseased arteries, n (%)
Single-artery 64 (52.5) 34 (47.9) 30 (58.8) 0.233
Multi-artery 58 (47.5) 37 (42.1) 21 (41.2)  
Initial TIMI flow grade, n (%)
0/1 95 (77.9) 48 (67.6) 47 (92.2) 0.001
2/3 27 (67.6) 23 (32.4) 4 (7.8)  
Final TIMI flow grade, n (%)
0/1 112 (91.8) 67 (94.4) 45 (88.2) 0.223
2/3 10 (8.2) 4 (5.6) 6 (11.8)  
Time from PCI to CMR (days) 5.2 (4.3 to 6.4) 5.1 (3.8 to 6.2) 5.2 (4.5 to 6.9) 0.275
LVEF (%) 36.7 ± 10.2 40.7 ± 9.7 31.2 ± 8.4  < 0.001
AAR (% LV) 28.3 (22.5 to 34.8) 25.3 (20.4 to 29.3) 34.8 (28.2 to 37.8)  < 0.001
IS (% LV) 22.3 (15.6 to 32.5) 18.4 (13.2 to 22.3) 27.3 (23.8 to 33.1)  < 0.001
MSI (%) 22.3 (13.9 to 37.2) 25.7 (14.9 to 44.8) 16.3 (8.8 to 22.2)  < 0.001
SYNTAX score 17.8 (11.0 to 22.0) 16.0 (10.0 to 18.0) 20.0 (15.8 to 22.3)  < 0.001
SYNTAX II score 33.6 ± 10.0 29.8 ± 8.8 38.8 ± 9.2  < 0.001
Gensini score 53.0 (36.0 to 80.0) 44.0 (32.0 to 58.0) 74.0 (50.5 to 81.5)  < 0.001
  1. Values are mean ± SD, number (%) or median (25th to 75th percentile)
  2. MVO Microvascular obstruction; GRACE The global registry of acute coronary events; CK Creatine kinase; CK-MB Creatine kinase isoenzyme; PRO-BNP Pro-B-type natriuretic peptide; CRP C-reaction protein; LDL-C Low density lipoprotein cholesterol; HDL-C High density lipoprotein cholesterol; PCI Percutaneous coronary intervention; LAD Left anterior descending coronary artery; LCX Left circumflex coronary artery; RCA Right coronary artery; TIMI Thrombolysis in myocardial infarction; CMR Cardiac magnetic resonance; LVEF Left ventricular ejection fraction; AAR Area at risk; IS Infarct size; MSI Myocardial salvage index