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Table 1 Characteristics of patients

From: Prediction of microvascular obstruction by coronary artery angiography score after acute ST-segment elevation myocardial infarction: a single-center retrospective observational study

Parameters

Total population (n = 122)

Non-MVO group (n = 71)

MVO group (n = 51)

p-value

Age (years)

60.6 ± 12.8

61.1 ± 14.1

59.8 ± 10.9

0.593

Male, n (%)

88 (72.1)

49 (69.0)

39 (76.5)

0.365

Heart rate (bpm)

79.8 ± 13.7

76.8 ± 12.9

82.9 ± 18.5

0.154

Systolic blood pressure (mmHg)

133.5 ± 20.7

133.0 ± 23.9

134.2 ± 15.5

0.733

Diastolic blood pressure (mmHg)

81.6 ± 14.1

80.6 ± 14.7

83.0 ± 13.2

0.345

Hypertension, n (%)

58 (47.5)

36 (50.7)

22 (43.1)

0.409

Diabetes, n (%)

32 (26.2)

17 (23.9)

15 (29.4)

0.498

Current Smoker, n (%)

27 (22.1)

13 (18.3)

14 (27.5)

0.230

Dyslipidemia, n (%)

16 (13.1)

10 (14.1)

6 (11.8)

0.708

GRACE score, n (%)

141.8 ± 29.0

133.2 ± 23.9

140.1 ± 31.2

0.188

Peak Troponin I (ng/ml)

23.7 (13.7 to 30.0)

15.8 (9.8 to 28.6)

30.0 (23.7 to 30.0)

 < 0.001

Peak CK (U/L)

2748.5 (1432.5 to 3817.5)

1925.5 (1138.5 to 3053.0)

3505.0 (2708.5 to 6920.3)

 < 0.001

Peak CK-MB (U/L)

270.0 (202.0 to 404.0)

211.0 (163.0 to 276.0)

346.0 (274.0 to 473.0)

 < 0.001

PRO-BNP (pg/mL)

815.0 (432.5 to 1996.5)

683.5 (427.8 to 933.0)

987.0 (515.8 to 3205.3)

0.026

CRP (mg/L)

6.9 (3.2 to 17.1)

4.8 (3.0 to 13.5)

9.9 (4.2 to 25.9)

0.008

Serum creatinine (umol/L)

58.6 (49.9 to 75.6)

58.4 (48.7 to 72.0)

58.9 (52.0 to 79.8)

0.144

Serum uric acid (umol/L)

301.2 (242.2 to 383.1)

291.6 (236.1 to 362.6)

307.8 (244.9 to 405.5)

0.234

Albumin (g/L)

37.3 ± 4.3

37.1 ± 4.4

37.6 ± 4.0

0.592

Plasma fibrinogen (g/L)

2.6 ± 1.0

2.6 ± 1.0

2.6 ± 0.9

0.882

D-Dimer (ng/ml)

89.7 (67.4 to 154.5)

84.7 (67.5 to 125.0)

99.0 (67.1 to 187.0)

0.075

Neutrophil (× 109/L)

7.9 (6.3 to 10.3)

7.9 (6.1 to 9.8)

8.5 (6.3 to 10.7)

0.165

Lymphocyte (× 109/L)

1.3 (0.9 to 1.6)

1.2 (0.9 to 1.6)

1.3 (1.0 to 1.5)

0.682

Total cholesterol (mmol/L)

4.1 (3.6 to 4.8)

4.2 (3.6 to 4.8)

3.9 (3.5 to 4.9)

0.267

Triglyceride (mmol/L)

1.2 (0.8 to 1.6)

1.1 (0.8 to 1.6)

1.4 (0.9 to 1.7)

0.075

LDL-C (mmol/L)

2.5 ± 0.6

2.5 ± 0.7

2.5 ± 0.5

0.458

HDL-C (mmol/L)

1.2 (1.0 to 1.6)

1.2 (1.0 to 1.6)

1.2 (1.0 to 1.5)

0.769

Heart failure Killip class, n (%)

I

91 (74.6)

55 (77.5)

36 (70.6)

0.389

 ≥ II

31 (15.4)

16 (12.5)

15 (29.4)

 

Time from symptom onset to PCI (h)

6.2 (4.5 to 9.3)

6.0 (5.0 to 9.0)

6.2 (4.0 to 11.3)

0.545

Culprit artery, n (%)

LAD

66 (54.1)

28 (39.4)

38 (74.5)

 < 0.001

LCX

9 (7.4)

6 (8.5)

3 (5.9)

0.592

RCA

47 (38.5)

37 (52.1)

10 (19.6)

 < 0.001

Number of diseased arteries, n (%)

Single-artery

64 (52.5)

34 (47.9)

30 (58.8)

0.233

Multi-artery

58 (47.5)

37 (42.1)

21 (41.2)

 

Initial TIMI flow grade, n (%)

0/1

95 (77.9)

48 (67.6)

47 (92.2)

0.001

2/3

27 (67.6)

23 (32.4)

4 (7.8)

 

Final TIMI flow grade, n (%)

0/1

112 (91.8)

67 (94.4)

45 (88.2)

0.223

2/3

10 (8.2)

4 (5.6)

6 (11.8)

 

Time from PCI to CMR (days)

5.2 (4.3 to 6.4)

5.1 (3.8 to 6.2)

5.2 (4.5 to 6.9)

0.275

LVEF (%)

36.7 ± 10.2

40.7 ± 9.7

31.2 ± 8.4

 < 0.001

AAR (% LV)

28.3 (22.5 to 34.8)

25.3 (20.4 to 29.3)

34.8 (28.2 to 37.8)

 < 0.001

IS (% LV)

22.3 (15.6 to 32.5)

18.4 (13.2 to 22.3)

27.3 (23.8 to 33.1)

 < 0.001

MSI (%)

22.3 (13.9 to 37.2)

25.7 (14.9 to 44.8)

16.3 (8.8 to 22.2)

 < 0.001

SYNTAX score

17.8 (11.0 to 22.0)

16.0 (10.0 to 18.0)

20.0 (15.8 to 22.3)

 < 0.001

SYNTAX II score

33.6 ± 10.0

29.8 ± 8.8

38.8 ± 9.2

 < 0.001

Gensini score

53.0 (36.0 to 80.0)

44.0 (32.0 to 58.0)

74.0 (50.5 to 81.5)

 < 0.001

  1. Values are mean ± SD, number (%) or median (25th to 75th percentile)
  2. MVO Microvascular obstruction; GRACE The global registry of acute coronary events; CK Creatine kinase; CK-MB Creatine kinase isoenzyme; PRO-BNP Pro-B-type natriuretic peptide; CRP C-reaction protein; LDL-C Low density lipoprotein cholesterol; HDL-C High density lipoprotein cholesterol; PCI Percutaneous coronary intervention; LAD Left anterior descending coronary artery; LCX Left circumflex coronary artery; RCA Right coronary artery; TIMI Thrombolysis in myocardial infarction; CMR Cardiac magnetic resonance; LVEF Left ventricular ejection fraction; AAR Area at risk; IS Infarct size; MSI Myocardial salvage index