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Table 4 Hazard ratios with corresponding 95% confidence intervals and p-values for the variables selected in the final model of the Cox proportional hazards regression multivariate analyses for cardiovascular disease mortality

From: The blood microbiome and its association to cardiovascular disease mortality: case-cohort study

Variable

Hazard ratio

Confidence interval 95%

p-value

Bacterial genus

   

Kocuria

3.60

1.62–7.78

0.002

Enhydrobacter

3.20

1.68–5.91

 < 0.001

Bacteroides

0.22

0.07–0.71

0.011

Paracoccus

0.34

0.15–0.77

0.010

Stenotrophomonas

0.35

0.16–0.77

0.009

Streptococcus

0.76

0.46–1.25

0.276

General health

   

Systolic blood pressure, 10 mmHg

1.10

0.99–1.24

0.066

Diabetes, yes

3.10

1.51–6.22

0.002

History of heart failure, yes

2.30

0.88–5.81

0.089

History of myocardial infarction, yes

2.20

1.25–4.01

0.007

Hypertensive medication, yes versus never

2.20

1.27–3.65

0.004

Hypertensive medication, yes versus previous

3.20

0.82–12.79

0.093

Lifestyle factor

   

Subjective health, not so good versus bad

0.20

0.08–0.50

0.001

Subjective health, good versus bad

0.13

0.05–0.32

 < 0.001

Subjective health, very good versus bad

0.06

0.02–0.19

 < 0.001

Excessive coffee consumption, > 3 cups per day

1.70

1.06–2.75

0.029