Table 1 GO analysis of significant DEGs in CA (Biological process)
Term | Enrichment Score | P-Value | Genes |
|---|---|---|---|
Cell division | 2.131764419 | 1.76E-04 | CCNA2, PTTG1, UBE2S, NCAPG2, CDK1, OIP5, ITGB3BP, MAD2L1, CKS1B, SPC25 |
Signal transduction | 2.402409842 | 2.86E-04 | LYN, ANGPT2, JUP, FST, PDE2A, IGFBP2, FGF2, GNG11, LYVE1, GULP1, GREM1, IL1RL1, MRC1, NAMPT, DEPDC1, SH3BP5, APOL3, ITGB3BP |
Positive regulation of angiogenesis | 2.402409842 | 0.004274532 | GREM1, ANGPT2, ANXA3, FGF2, TGFBR2 |
Regulation of transcription involved in G1/S transition of mitotic cell cycle | 1.428531084 | 0.007567953 | RRM2, PCNA, CDK1 |
Anaphase-promoting complex-dependent catabolic process | 2.131764419 | 0.010465853 | PTTG1, UBE2S, CDK1, MAD2L1 |
Signal transduction by protein phosphorylation | 1.328614154 | 0.026187945 | LYN, TGFB2, TGFBR2 |
Response to drug | 1.328614154 | 0.030291549 | LYN, TGFB2, IGFBP2, CDK1, HMGB2, TGFBR2 |
Positive regulation of cell proliferation | 2.402409842 | 0.050823527 | LYN, GREM1, TGFB2, NAMPT, AKR1C2, FGF2, TGFBR2 |
DNA replication | 1.428531084 | 0.05923696 | RFC3, RRM2, PCNA, CDK1 |
G1/S transition of mitotic cell cycle | 1.428531083 | 0.11556745 | RRM2, PCNA, CDK1 |