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Table 4 The Hardy–Weinberg equilibrium for alcohol intake group among cases and controls, and the association of ALDH2 rs671 with acute myocardial infarction in alcohol intake subjects

From: Association of functional variant of aldehyde dehydrogenase 2 with acute myocardial infarction of Chinese patients

ALDH2 rs671

 

Case

Control

Total

Genotype

Number

%

Number

%

Number

%

GG

656

72.81

726

75.78

1382

74.34

GA

221

24.53

217

22.65

438

23.56

AA

24

2.66

15

1.57

39

2.10

Total

901

100

958

100

1859

100

HWp

0.303

 

0.777

 

0.532

 

G

1533

85.07

1669

87.11

  

A

269

14.93

247

12.89

  

Model

χ2

OR (95% CI)

p

  

AA/GG

3.009

1.771 (0.921–3.404)

0.08278

  

GA/GG

1.19

1.127 (0.909–1.397)

0.27527

  

AA + GA/GG

2.154

1.169 (0.949–1.439)

0.14218

  

AA/GA/GG

3.169

1.183 (0.983–1.423)

0.07507

  
 

3.548

1.196 (0.993–1.440)

0.05963

adjusted by sex,age,bmi

 

1.294

1.128 (0.917–1.387)

0.25539

adjusted by sex,age,bmi,ApoB/ApoA1

A/G

3.222

1.186 (0.984–1.428)

0.07266