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Table 3 The Hardy–Weinberg equilibrium in subjects with no alcohol intake among cases and controls, and the association of ALDH2 rs671 with acute myocardial infarction in no alcohol intake subjects

From: Association of functional variant of aldehyde dehydrogenase 2 with acute myocardial infarction of Chinese patients

ALDH2 rs671

 

Case

Control

Total

Genotype

Number

%

Number

%

Number

%

GG

881

61.87

1126

67.75

2007

65.04

GA

478

33.57

475

28.58

953

30.88

AA

65

4.56

61

3.67

126

4.08

Total

1424

100

1662

100

3086

100

HWp

0.920

 

0.218

 

0.337

 

G

2240

78.65

2727

82.04

  

A

608

21.35

597

17.96

  

Model

χ2

OR (95% CI)

p

  

AA/GG

2.841

1.362 (0.950–1.953)

0.09187

  

GA/GG

10.2

1.286 (1.102–1.501)

0.00140

  

AA + GA/GG

11.667

1.295 (1.116–1.502)

0.00064

  

AA/GA/GG

10.973

1.236 (1.090–1.401)

0.00092

  
 

11.705

1.247 (1.099–1.415)

0.00062

adjusted by sex,age,bmi

 

5.44

1.182 (1.027–1.360)

0.01968

adjusted by sex,age,bmi,ApoB/ApoA1

A/G

11.206

1.240 (1.093–1.406)

0.00082