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Table 2 The Hardy–Weinberg equilibrium in all cases and controls, and the association of ALDH2 rs671 with acute myocardial infarction subjects

From: Association of functional variant of aldehyde dehydrogenase 2 with acute myocardial infarction of Chinese patients

ALDH2 rs671

 

Case

Control

Total

Genotype

Number

%

Number

%

Number

%

GG

1537

66.11

1852

70.69

3389

68.53

GA

699

30.06

692

26.41

1391

28.13

AA

89

3.83

76

2.90

165

3.34

Total

2325

100

2620

100

4945

100

HWp

0.393

 

0.245

 

0.131

 

G

3773

81.14

4396

83.89

  

A

877

18.86

844

16.11

  

Model

χ2

OR (95% CI)

p

  

AA/GG

4.674

1.411 (1.031–1.931)

0.03062

  

GA/GG

9.507

1.217 (1.074–1.379)

0.00205

  

AA + GA/GG

11.98

1.236 (1.096–1.394)

0.00054

  

AA/GA/GG

12.709

1.206 (1.088–1.337)

0.00037

  
 

13.239

1.212 (1.093–1.345)

0.00027

adjusted by sex,age,bmi

 

14.952

1.229 (1.107–1.364)

0.00011

adjusted by sex,age,bmi,drink

 

15.769

1.236 (1.114–1.373)

0.00008

adjusted by sex,age,bmi,drinktimes

 

13.995

1.219 (1.099–1.352)

0.00018

adjusted by drink

 

14.585

1.224 (1.104–1.359)

0.00014

adjusted by drinktimes

 

5.467

1.148 (1.023–1.288)

0.01938

adjusted by sex,age,bmi,ApoB/ApoA1

A/G

12.994

1.211 (1.091–1.343)

0.00031