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Table 1 Case information of the cover-disc in 11 dogs without concavity revealed by TEE

From: The healing response of LAMax LAAC™ left atrial appendage occluder in a canine model: the potential influence of the implantation technique on the healing response

Group Case No Device model* LAA orifice covered by cover-disc monitored by TEE Peri-device flow CDFI Post-LAAC (mm) Neo-intimal coverage of LAA occluder’s atrial-surface inspected by gross examination
      < 24 h 1 m 2 m 3 m  
1 month 8 1824 Partially, gap 0 0 Partially, except area at 60° near MA
9 2430 Partially, gap 0 0 Partially, except area at 120° near MA
11 1824 Partially, Over the orifice 5 0 Partially, anchor part blocked LAA orifice, none detectable hole was found from LA to LAA
2 months 14 1824 Partially, gap 2 0 0 Partially, except the area at 0° near MA, none detectable hole was found from LA to LAA
3 months 18 1824 Partially, pushed MA 0 0 0 0 Fully, MA compression by cover-plate with granulation tissue
19 2127 Partially, over the orifice 0 0 0 0 Partially, anchor part blocked small lobe, none detectable hole was found from LA to LAA
21 1824 Partially, gap 2 2 2 2 Fully, the left edge of cover-plate inside LAA, an irregular fissure along the cover plate's edge was found and passed with an 18-gauge hypodermic needle from LA to LAA
23 2127 Partially,Over the orifice 3 3 0 0 Partially, anchor part blocked LAA orifice, none detectable hole was found from LA to LAA
24 1824 Partially, large gap 2 2 2 2 Fully, left edge of cover-plate inside LAA, an irregular hole was found from LA to LAA and passed with an 18-gauge hypodermic needle
6 months 25 2133# Partially, pushed MA 0 0 0 0 Fully, MA compression with granulation tissue, pulmonary venous partial obstruction
27 2430 Partially, pushed MA 0 0 0 0 Fully, MA compression with granulation tissue
  1. *, the first two digits of LAMax device model are the diameter of anchor part, while the last two digits are the diameter of the cover-plate part; #, LAMax plus device with a special-designed cover-plate with 12 mm larger in diameter than the anchor; LAA, left atrial appendage; MA, mitral annulus