Fig. 4

Histological examination. A Sagittal section through the center of the implanted device and the left atrial appendage in a dog at 6 months post-implantation (scale bar: 2 mm). B A close-up microscopic view showed the neointimal coverage over the atrial surface of the device, “*” indicates the PET membrane (scale bar: 0.5 mm). The tight sealing of the cover-plate with the LAA wall is shown (scale bar: 0.5 mm). C A close-up microscopic view showed the LAA wall without inflammation. Toluidine Blue O stain (1%)