Fig. 2

Anatomical examination. A The cover-disc was tightly placed on the LAA ostium, neo-intima completely covered the atrial surface of the cover-disc and the central screw hub at 1-month follow up after LAAC. B The cover-disc was loosely placed on the LAA ostium; although the neo-intima completed covered the atrial surface of the cover plate, the area closed to MA at 60° was not completely covered by neo-intima. C The neo-intima completely covered the surface of cover-disc without thrombus but did not cover the central screw hub. In the part of MA in contact with the disc, granulomas were found. D, E The anchor was placed in a small lobe of the bi-lobular LAA; the atrial surface of the cover-disc was completely covered by neo-intima. In the part of MA contacted with the cover-disc, granulomas were found. F In one dog with the residual flow at the group of 3-months after LAAC, the atrial surface of cover-disc was completely covered by neo-intima; the part of the disc at 0° connected with LA wall tightly, while the part at 180° did not connect with LA wall, and there was an irregular fissure between LA and LAA. By examining the MA side, it was found that the disc did not pull into the LAA ostium, and there was an irregular fissure between LA and LAA. In addition, an 18-gauge hypodermic needle was able to get through the hole from LA to LAA