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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Agonist-induced Piezo1 activation promote mitochondrial-dependent apoptosis in vascular smooth muscle cells

Fig. 2Fig. 2

Piezo1 induced VSMCs apoptosis by activating the mitochondrial apoptotic pathway. Cells were treated with Yoda1 (10, 20, 30 μm) for 24 h. (A) The detection of cell viability. (B, C) The apoptosis rate of each group. (D) MMP of each group was determined. (E) Quantitative analysis of the MMP. (F, H) Western blot analysis of several apoptotic-related protein expression levels. (G, I) Relative expression statistics of Western blot analysis. *P < 0.05 and **P < 0.01 versus Control

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