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Table 1 Baseline characteristics and CAD risk factors among the study participants

From: Identification of a circulating microRNAs biomarker panel for non-invasive diagnosis of coronary artery disease: case–control study

Variable Controls CAD cases P-value Odds ratio (95% CI)
Aget 38.34 ± 11.90 54.93 ± 9.56 < 0.001***
Age groupM
> 55 years 11 (15.1%) 34 (46.6%) < 0.001*** Reference
< 55 years 62 (84.9%) 39 (53.4%) 4.9 (2.2–10.8)
GenderM
Males 52 (71.2%) 55 (75.3%) > 0.05 (ns) Reference
Females 21 (28.8%) 18 (24.7%) 1.2 (0.6–2.6)
SmokingM
Smoker 21 (28.8%) 42 (57.5%) < 0.001*** Reference
Non-smoker 52 (71.2%) 31 (42.5%) 3.4 (1.7–6.7)
Family historyM
Positive 25 (34.2%) 45 (61.6%) < 0.001*** Reference
Negative 48 (65.8%) 28 (38.4%) 3.1 (1.6–6.1)
DyslipidemiaM
Dyslipidemia 3 (4.1%) 59 (80.8%) < 0.001*** Reference
No dyslipidemia 70 (95.9%) 14 (19.2%) 98.3 (27–358.7)
ObesityM
Obese 21 (28.8%) 36 (49.3%) 0.011* Reference
Non-obese 52 (71.2%) 37 (50.7%) 2.4 (1.2–4.8)
BMIt 27.69 ± 3.99 30.16 ± 5.68 0.003**
  1. *, **, *** Significant at p < 0.05, < 0.01, < 0.001; ns, nonsignificant at p > 0.05
  2. tindependent t-test between study and control groups (parametric)
  3. MMann–Whitney test between study and control groups (non-parametric)