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Table 1 Baseline characteristics and CAD risk factors among the study participants

From: Identification of a circulating microRNAs biomarker panel for non-invasive diagnosis of coronary artery disease: case–control study

Variable

Controls

CAD cases

P-value

Odds ratio (95% CI)

Aget

38.34 ± 11.90

54.93 ± 9.56

< 0.001***

Age groupM

> 55 years

11 (15.1%)

34 (46.6%)

< 0.001***

Reference

< 55 years

62 (84.9%)

39 (53.4%)

4.9 (2.2–10.8)

GenderM

Males

52 (71.2%)

55 (75.3%)

> 0.05 (ns)

Reference

Females

21 (28.8%)

18 (24.7%)

1.2 (0.6–2.6)

SmokingM

Smoker

21 (28.8%)

42 (57.5%)

< 0.001***

Reference

Non-smoker

52 (71.2%)

31 (42.5%)

3.4 (1.7–6.7)

Family historyM

Positive

25 (34.2%)

45 (61.6%)

< 0.001***

Reference

Negative

48 (65.8%)

28 (38.4%)

3.1 (1.6–6.1)

DyslipidemiaM

Dyslipidemia

3 (4.1%)

59 (80.8%)

< 0.001***

Reference

No dyslipidemia

70 (95.9%)

14 (19.2%)

98.3 (27–358.7)

ObesityM

Obese

21 (28.8%)

36 (49.3%)

0.011*

Reference

Non-obese

52 (71.2%)

37 (50.7%)

2.4 (1.2–4.8)

BMIt

27.69 ± 3.99

30.16 ± 5.68

0.003**

  1. *, **, *** Significant at p < 0.05, < 0.01, < 0.001; ns, nonsignificant at p > 0.05
  2. tindependent t-test between study and control groups (parametric)
  3. MMann–Whitney test between study and control groups (non-parametric)