Table1 Characteristics of include studies
Author /year | region | Size | Population | Follow-up | Age | Study type | object | AFR | RR/HR | Adjusted | Measure | Quality assessment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nagashima/2011 [22] | Japan | 40 | 24 PAF 16 Per AF | 0.85 y | 58.0 y | Retrospective | LA-EAT volumes | 15(37.5%) | 7.15 (3.03–11.3) | Age, BMI, HbA1c, HDL-C, LDL-C, TG | CT | high-quality |
Masuda/2015 [23] | Japan | 53 | 22 PAF 31 Per AF | 1.33 y | 61.5 y | Retrospective | LA-EAT volumes | 36(67.9%) | 1.06 (1.03–1.10) | PAF rate, Left atrial volume, Radio-frequency application time | CT | high-quality |
Stojanovska/2015 [24] | United States | 169 | 94 PAF 75 Per AF | 3.2 y | 64.0 y | Retrospective | EAT volumes | 78(46%) | 1.009 (1.001–1.01) | age, gender, BMI | CT | high-quality |
Canpolat/2016 [13] | Turkey | 234 | 190 PAF 44 Per AF | 1.7 y | 54.0 y | Retrospective | EAT thickness | 45(19.2%) | 1.36 (1.10–1.66) | Age, Dyslipidemia, Non-paroxysmal AF rate, Duration of AF, EHRA score, LA diameter, hs-CRP | Echo | high-quality |
Chao/2013 [14] | China | 283 | 227 PAF 56 Per AF | 1.3 y | 54.6 y | Retrospective | EAT thickness | 95(33.6%) | 2.863 (2.112–3.882) | Non-paroxysmal AF rate, CHADS2 score, LA diameter | Echo/CT | high-quality |
Maeda/2018 [25] | Japan | 218 | 143 PAF 78 Per AF | 1.45 y | 64.0 y | Retrospective | EATVi | 61(28%) | 1.02 (1.00–1.03) | Non-paroxysmal AF rate, Body height, eGFR, IVS thickness, Septal E/E’ | CT | high-quality |
Sanghai/2018 [15] | United States | 274 | 189 PAF 85 Per AF | 1.0 y | 61.0 y | Retrospective | iLAEAT | 109(40%) | 2.93 (1.34–6.43) | CHA2DS2Vascscore BMI, LA Volume, LV mass index, average E/e’ | CT | high-quality |
Kawasaki/2020 [16] | Japan | 64 | 64 PAF | 1.0 y | 70.7 y | Retrospective | peri-atrial EAT/TEA thickness | 14(21.9%) | 4.822(1.209–32.809) | Calcium channel blockers, Delta WR | CT | high-quality |
Mahdiui/2021 [17] | Hungary | 460 | 354 PAF 106 Per AF | 1.5 y | 61.0 y | Retrospective | Posterior LAEA thickness | 168(37%) | 1.01 (0.97–1.04) | Age, sex, AF type, BMI, antiarrhythmic drugs, LVEF < 50%, E/A-ratio, LA volume | CT | high-quality |
Romanov/2021 [18] | Russian | 45 | 15 PAF 30 Per AF | 1.0 y | 55.2 y | Retrospective | peri-atrial EAT volumes | 9(20%) | 1.02 (0.99–1.05) | NA | CT | medium-quality |