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Table 1 Characteristics of hospitalizations, rhythm control procedure utilization, and mortality outcome for primary atrial fibrillation (patient level, financial, and hospital-level) from 2012 to 2015 in cancer vs. non-cancer patients

From: Length of stay and cost of care associated with admissions for atrial fibrillation among patients with cancer

Variable

Breast cancer (n = 53,800)

P value*

Lung cancer (n = 29,535)

P value*

Colon cancer (n = 22,525)

P value*

Prostate cancer (n = 39,145)

P value*

Lymphoma (n = 19,025)

P value*

Non-cancer (n = 1,324,335)

Patient characteristics

           

 Age, years (mean ± SE)

77.4 ± 0.1

 < .001

73.5 ± 0.1

 < .001

78.3 ± 0.2

 < .001

76.8 ± 0.1

 < .001

74.0 ± 0.2

 < .001

69.5 ± 0.04

 Women, %

99.1

 < .001

46.5

 < .001

56.5

 < .001

  

48.3

 < .001

51.6

 Race, %

 

 < .001

 

 < .001

 

 < .001

 

 < .001

 

 < .001

 

  White

87.8

 

87.0

 

86.3

 

85.2

 

87.3

 

81.9

  Black

6.0

 

6.8

 

6.4

 

8.5

 

5.6

 

8.1

  Hispanic

3.3

 

2.9

 

4.2

 

3.7

 

3.8

 

5.8

  Asian or Pacific Islander

1.1

 

1.4

 

1.1

 

0.8

 

1.3

 

1.5

  Native American

0.2

 

0.4

 

0.3

 

0.2

 

0.4

 

0.4

  Other

1.5

 

1.5

 

1.8

 

1.6

 

1.7

 

2.2

 Income quartiles

 

 < .001

 

.0001

 

.0001

 

 < .001

 

 < .001

 

  0–25

23.5

 

28.8

 

25.6

 

23.2

 

21.5

 

27.6

  26–50

26.0

 

26.7

 

28.2

 

26.2

 

26.6

 

26.8

  51–75

25.4

 

24.9

 

24.2

 

23.8

 

25.2

 

24.3

  76–100

25.1

 

19.6

 

22.0

 

26.8

 

26.8

 

21.2

Payment source (%)

 

 < .001

 

 < .001

 

 < .001

 

 < .001

 

 < .001

 

 Medicare

86.1

 

78.7

 

86.0

 

83.6

 

79.4

 

65.3

 Medicaid

1.6

 

4.3

 

1.8

 

1.0

 

2.2

 

5.5

 Private

11.1

 

14.4

 

10.2

 

13.0

 

16.6

 

23.5

 Self-pay

0.5

 

0.8

 

0.8

 

0.5

 

0.6

 

3.3

 No charge

0.1

 

0.1

 

0.1

 

0.03

 

0.2

 

0.4

 Others

0.7

 

1.7

 

1.2

 

1.9

 

1.0

 

2.1

Comorbidities (%)

           

Cardiomyopathy

8.8

 < .001

6.6

 < .001

8.7

 < .001

10.4

 < .001

11.8

.0001

11.7

 Hypertension

77.7

 < .001

69.8

 < .001

77.9

 < .001

77.6

 < .001

70.0

 < .001

74.2

 Diabetes

26.4

 < .001

26.5

 < .001

29.4

0.19

27.2

 < .001

26.3

 < .001

28.8

 Obesity

12.5

 < .001

8.0

 < .001

11.0

 < .001

10.5

 < .001

10.3

 < .001

18.4

 Dyslipidemia

50.1

 < .001

45.3

 < .001

47.6

0.38

56.4

 < .001

43.4

 < .001

47.6

 Coronary artery disease

24.9

 < .001

32.9

 < .001

32.7

 < .001

41.2

 < .001

29.5

.12

30.1

 Prior myocardial infarction

6.5

.005

9.0

 < .001

9.1

 < .001

10.2

 < .001

7.1

.06

7.4

 Prior coronary bypass grafting

4.7

 < .001

7.8

.0002

8.4

 < .001

12.4

 < .001

7.3

.82

7.3

 Peripheral vascular disease

6.5

.03

11.5

 < .001

8.9

 < .001

10.2

 < .001

7.4

.80

7.0

 Prior TIA/stroke

12.4

 < .001

8.5

.79

12.5

 < .001

11.8

 < .001

9.2

.36

9.7

 Chronic renal disease

15.0

.37

14.5

.30

20.5

 < .001

22.0

 < .001

23.2

 < .001

15.3

 Chronic lung disease

23.4

.005

56.6

 < .001

24.9

.003

23.2

 < .001

22.4

.14

22.7

 Coagulation disorder

3.5

.26

7.0

 < .001

4.8

 < .001

5.8

 < .001

11.3

 < .001

3.3

 Smoker

23.4

 < .001

57.3

 < .001

29.2

.17

36.1

 < .001

26.9

.0001

28.0

Total elixhauser’s comorbidities

 

 < .001

 

 < .001

 

 < .001

 

 < .001

 

 < .001

 

 0

4.7

 

1.0

 

3.9

 

5.4

 

1.7

 

8.6

 1

17.9

 

7.3

 

15.3

 

18.7

 

9.2

 

21.4

 2

24.8

 

18.1

 

22.6

 

24.6

 

19.2

 

25.4

  ≥ 3

52.5

 

73.7

 

58.2

 

51.4

 

70.0

 

44.6

 Elixhauser’s mortality score (mean ± SE)

4.7 ± 0.1

 < .001

12.4 ± 0.1

 < .001

6.5 ± 0.1

 < .001

6.3 ± 0.1

 < .001

10.3 ± 0.2

 < .001

2.4 ± 0.02

 Teaching hospital (%)

52.3

.0001

50.9

.02

50.1

.01

54.0

 < .001

56.2

 < .001

51.2

Bed size, (%)

 

.07

 

.66

 

.57

 

 < .001

 

.09

 

 Small

16.0

 

16.2

 

15.9

 

15.2

 

15.8

 

16.7

 Medium

28.6

 

28.1

 

28.2

 

28.2

 

27.4

 

28.4

 Large

55.4

 

55.7

 

55.9

 

56.6

 

56.8

 

54.9

Region (%)

 

 < .001

 

 < .001

 

 < .001

 

 < .001

 

 < .001

 

 Northeast

21.9

 

20.9

 

22.5

 

22.9

 

23.1

 

20.7

 Midwest

25.5

 

25.6

 

26.8

 

26.0

 

24.7

 

24.4

 South

37.0

 

41.0

 

36.7

 

36.0

 

36.4

 

40.1

 West

15.7

 

12.6

 

14.1

 

15.1

 

15.8

 

14.8

Rhythm control procedure

           

 DCCV

10.8

 < 0.001

8.2

 < 0.001

10.4

 < 0.001

13.6

 < 0.001

11.4

 < 0.001

15.6

 AF ablation

3.6

 < 0.001

2.5

 < 0.001

2.9

 < 0.001

4.7

 < 0.001

3.7

 < 0.001

5.7

Mortality

0.9

0.7

3.2

 < 0.001

1.1

0.001

0.8

0.08

2.3

 < 0.001

0.9

  1. AF, atrial fibrillation; DCCV, DC cardioversion
  2. *P values presented in the column next to the values for each cancer is versus non-cancer, the values of which are presented in the last column
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