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Table 2 Hazard ratios (HR) and 95% confidence interval for one-year all-cause mortality of DAPT adherence estimated from multivariate Cox proportional hazard model (N = 2019)

From: The effects of dual antiplatelet therapy (DAPT) adherence on survival in patients undergoing revascularization and the determinants of DAPT adherence

Variables

Multivariate cox PH model

HR

95%CI

P value

DAPT adherence versus non-adherence

0.52

(0.36, 0.76)

 < 0.001

Age (years)

1.05

(1.03, 1.07)

 < 0.001

Male versus female

0.91

(0.56, 1.47)

0.69

Hypertension versus no hypertension

1.03

(0.68, 1.54)

0.90

Antihypertensive treatment versus no treatment

0.08

(0.05, 0.14)

 < 0.001

Diabetes versus no diabetes

1.43

(0.97, 2.1)

0.07

Eligible CAD type

   

 Chronic stable angina/positive stress test

Ref

Ref

Ref

 Previous myocardial infraction

1.56

(0.89, 2.71)

0.12

 Acute coronary syndrome

0.99

(0.65, 1.51)

0.96

No smoking versus smoking

1.09

(0.71, 1.67)

0.71

Underwent PCI out of versus in Mumbai

0.71

(0.45, 1.13)

0.15

Middle school and above versus none or up to primary school

1.36

(0.91, 2.03)

0.14

Employed versus unemployed

1.12

(0.73, 1.72)

0.61

Stent location

   

 LAD

Ref

Ref

Ref

 RCA

0.43

(0.22, 0.83)

0.01

 LCX

0.42

(0.16, 1.05)

0.06

Multiple locations

0.75

(0.43, 1.33)

0.33

Stent type

   

 BMS

Ref

Ref

Ref

 DES

0.97

(0.64, 1.45)

0.86

 DES and BMS

0.47

(0.14, 1.55)

0.21

Year of PTCA

   

 2012

Ref

Ref

Ref

 2013

0.92

(0.53, 1.6)

0.77

 2014

1.66

(0.88, 3.12)

0.12

 2015

2.25

(1.20, 4.23)

0.01

Total length of stents

1.01

(1.00, 1.03)

0.02

Total number of stents (mm)

1.04

(0.68, 1.59)

0.85

  1. BMS, bare-metal stent; DES, drug-eluting stent; LAD, left anterior descending artery; LCX, left circumflex artery; RCA, right coronary artery; PTCA, percutaneous transluminal coronary angioplasty
  2. Reference group: Female; no diabetes; no hypertension; not having antihypertensive treatment; chronic stable angina/positive stress test; current/past smoker; underwent intervention in Mumbai; none or up to primary school; not employed; only stent on LAD; only stent with BMS; PTCA in 2012
  3. Model adjusted for age, sex, hypertension, diabetes, eligible CAD type, status of tobacco use, education level, employment status, revascularization in Mumbai or not, sent location, stent type, year of PCI, total number of stents, total stent length