Fig. 2
From: Clinical genetic testing in four highly suspected pediatric restrictive cardiomyopathy cases
Representative images of M-mode echocardiography and diastolic function of left ventricles. E: peak mitral flow velocity in early diastole; A: peak mitral flow velocity in late diastole. IVRT: isovolumic relaxation time. E′: peak velocity of mitral annulus in early diastole; a′: peak velocity of mitral annulus in late diastole. a (case 1), b (case 2), c (case 4): M-mode echocardiography showed no abrupt septal movement (‘notch’ or ‘bounce’ in early diastole, or septal movement toward left ventricle in inspiration). d (case 1), e (case 2), f (case 4): Mitral flow velocity by pulsed Doppler echocardiography showing reduced cardiac diastolic function. g (case 1), h (case 4): Tissue velocity imaging of mitral annulus showing reduced cardiac diastolic function