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Table 1 Baseline characteristics of the study population

From: Effects of Sacubitril/Valsartan on biomarkers of fibrosis and inflammation in patients with heart failure with reduced ejection fraction

Patients, N = 26

 

Age, years

69.8 ± 2.3

Men, n (%)

20 (77%)

Ischemic etiology, n (%)

12 (46%)

NYHA class III, n (%)

26 (100%)

SBP (mmHg)

126.8 ± 3.1

DBP (mmHg)

77.5 ± 2.1

Creatinine (mg/dl)

1.1 ± 0.1

eGFR (ml/min/1.73m2)

44.3 ± 4.1

Na+ (mEq/L)

139.9 ± 0.5

K+ (mEq/L)

4.4 ± 0.1

Smoking history, n (%)

13 (50%)

Diabetics, n (%)

10 (38.4%)

Hypertension, n (%)

16 (62%)

Hyperlipidemia, n (%)

16 (62%)

BB, n (%)

26 (100%)

MRA, n (%)

26 (100%)

Diuretics, n (%)

26 (100%)

Sinus Rythm, n (%)

17 (65%)

Atrial Fibrilation, n (%)

4 (15%)

ICD, n (%)

6 (23%)

CRT-D, n (%)

8 (31%)

LNEF (%)

29.5 ± 1.0

LVESVi (ml/m2)

38.6 ± 8.7

  1. NYHA New York Heart Association; SBP systolic blood pressure; DBP diastolic body pressure; eGFR estimated glomerular filtration rate calculated with Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula; Na+ sodium; K+ potassium; BB beta-blockers; ICD implantable cardioverter defibrillator; MRA mineralcorticoid receptor antagonist; CRT-D cardiac resynchronization therapy—defibrillator; LVEF Left ventricular ejection fraction; LVESVi Indexed Left ventricular end-systolic volume. Values are presented as absolute numbers, percentages and mean ± standard error (SE)