Lymphocyte-to-monocyte ratio associated with severe post-stenotic aortic dilation in a case–control study

Table 2 Clinical characteristics of patients with high-LMR or low-LMR

	High-LMR	Low-LMR	p value
Patient population (n)	142	66
Demographic data
Age (years)	59 (13)	63 (8.25)	0.005
Sex, male (n)	86 (60.6%)	49 (74.2%)	0.048
Medical history
Hypertension (n)	42 (29.6%)	33 (50.0%)	0.004
Smoking (n)	62 (43.7%)	32 (48.5%)	0.488
Diabetes (n)	14 (9.9%)	4 (6.1%)	0.372
Post-calcific stenotic aortic dilatation (n)	28 (19.7%)	29 (43.9%)	< 0.001
Maximal diameter of the ascending aorta (cm)	4.35 (1.03)	4.76 (1.60)	0.003
Tricuspid aortic valve(n)	61 (43.0%)	52 (78.8%)	< 0.001
Baseline echocardiography
LVEDD (cm)	5.41 (1.43)	6.29 (1.41)	< 0.001
LVEF (%)	60 (7)	58 (7.5)	0.031
Preoperative laboratory tests
Leukocyte (10⁹/L)	5.74 (1.93)	6.16 (1.90)	0.020
Neutrophil (10⁹/L)	3.33 (1.48)	3.73 (1.26)	0.004
Platelet (10⁹/L)	193 (69)	187 (85.25)	0.818
Monocyte (10⁹/L)	0.47 (0.20)	0.79 (0.43)	< 0.001
Lymphocyte (10⁹/L)	1.88 (0.51)	1.54 (0.67)	< 0.001
LDL-C (mmol/L)	2.87 (1.18)	2.68 (1.12)	0.101
CRP (mg/L)	0.77 (1.43)	1.18 (2.07)	0.134
MPV (fl)	10.90 (1.30)	10.60 (1.15)	0.287

The categorical variables in the table are presented by the number of cases (with percentage) and the continuous variables are expressed by the median (with interquartile range) or mean (with standard deviation)
p values were the results of unpaired t-test or Mann–Whitney U test for continuous variables, and χ2 test or Fisher’s exact test for categorical variables
p value: Compare the overall patients with Low-LMR or High-LMR
LVEDD left ventricular end diastolic diameter, LVEF left ventricular ejection fraction, LMR lymphocyte-to-monocyte ratio, LDL-C low density lipoprotein cholesterol, CRP C-reaction protein, MPV mean platelet volume

ISSN: 1471-2261