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Table 3 Association between carotid plaque characteristics and the type of ischemic events

From: Comparison of carotid atherosclerotic plaque characteristics between symptomatic patients with transient ischemic attack and stroke using high-resolution magnetic resonance imaging

 

Stroke subtype of ischemic events a

Univariate model

Multivariate model 1b

Multivariate model 2c

OR (95%CI)

p

OR (95%CI)

p

OR (95%CI)

p

Morphology of carotid plaque

Mean lumen area

0.99 (0.98–1.03)

0.265

0.98 (0.97–1.02)

0.201

-

-

Mean wall area

1.04 (1.01–1.07)

0.005

1.04 (1.01–1.07)

0.018

-

-

Mean WT

6.53 (2.07–20.57)

0.001

5.52 (1.65–18.45)

0.006

-

-

Stenosis

1.02 (0.99–1.04)

0.058

1.02 (0.99–1.04)

0.059

-

-

Wall volume

1.00 (1.00–1.00)

0.097

1.00 (1.00–1.00)

0.252

-

-

Maximum NWI

1.61 (1.06–2.44)

0.024

1.56 (1.02–2.38)

0.038

-

-

Components of carotid plaque

Presence of LNRC

1.68 (0.72–3.95)

0.234

1.61 (0.67–3.86)

0.287

1.47 (0.61–3.57)

0.389

Presence of IPH

1.53 (0.87–2.70)

0.140

1.43 (0.79–2.59)

0.239

1.22 (0.66–2.27)

0.519

Presence of Ca

1.21 (0.72–2.02)

0.469

1.08 (0.62–1.87)

0.792

1.02 (0.58–1.78)

0.944

%Volume of LNRC d

1.52 (1.11–2.07)

0.007

1.51 (1.10–2.07)

0.011

1.41 (1.01–1.96)

0.041

%Volume of IPH d

1.41 (0.59–3.39)

0.444

1.19 (0.48–2.97)

0.711

0.97 (0.38–2.47)

0.952

%Volume of CAd

1.47 (0.66–3.29)

0.345

1.31 (0.56–3.06)

0.540

1.00 (0.41–2.46)

0.994

  1. aTIA and ischemic stroke were respectively coded as 0 and 1 in the logistic regression analysis
  2. bModel 1 was adjusting for age, sex, BMI, and diabetes mellitus
  3. cModel 2 contains model 1 with further adjustment for maximum NWI
  4. dIncrement of 10%; OR: odds ratio; WT: wall thickness; NWI: normalized wall index; LRNC: lipid-rich necrotic-core; IPH: intraplaque hemorrhage; CA: calcification