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Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: H3K9me2 regulation of BDNF expression via G9a partakes in the progression of heart failure

Fig. 3

Inhibition of G9a attenuates the myocardial injury in rats with HF. A Detection of G9a expression in rats by RT-qPCR. B Echocardiographic assessment of cardiac function in rats. C Myocardial damage in rats examined using TTC staining. D The pathological changes in the myocardial tissues of rats measured using HE staining. E Detection of CK-MB and cTnI in the serum of rats measured using ELISA. F Changes of inflammatory factors IL-6 and TNF-α in rats detected by ELISA. G Apoptosis in myocardial tissues of rats measured using TUNEL assay. H Changes of α-SMA in myocardial tissues of rats by immunohistochemistry. Data are expressed as mean ± SD (n = 6). Three or more groups were compared by one-way or two-way ANOVA and Tukey's post hoc test. *p < 0.05, **p < 0.01, ***p < 0.001

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