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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: H3K9me2 regulation of BDNF expression via G9a partakes in the progression of heart failure

Fig. 2

Knockdown of G9a inhibits apoptosis and injury in OGD-treated cardiomyocytes. A The mRNA expression of G9a in cells detected by RT-qPCR. B The proliferative activity of cells measured by CCK8 assay. C The apoptotic activity of cells measured using flow cytometry. D Detection of cytotoxicity of cells by LDH cytotoxicity kits. E The levels of fibrosis-related factors α-SMA and FN1 in cells examined using Western blot (Uncropped protein blots are provided in the Additional file 1). Data are expressed as mean ± SD. Each experiment was repeated at least three times. Three or more groups were compared by one-way or two-way ANOVA and Tukey's post hoc test. *p < 0.05, **p < 0.01

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