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Table 1 Results of the blood gas analysis

From: Impact of the inspiratory oxygen fraction on the cardiac output during jugulo-femoral venoarterial extracorporeal membrane oxygenation in the rat

value Group t0 t4 t8 t12 t16
pH A 7.42 [7.38–7.43] 7.48 [7.46–7.51] 7.48 [7.47–7.50] 7.45 [7.44–7.48] 7.44 [7.42–7.45]
  B 7.40 [7.37–7.42] 7.47 [7.47–7.52] 7.47 [7.46–7.51] 7.45 [7.43–7.48] 7.42 [7.41–7.46]
  C 7.39 [7.37–7.40] 7.19 [7.18–7.24] *** ### 7.15 [7.09–7.18] *** ###   
Bic A 25.9 [24.4–26.9] 27.0 [26.3–27.8] 26.1 [22.7–27.0] 24.7 [23.7–26.4] 23.8 [22.8–24.2]
(mmol/l) B 25.2 [24.9–27.2] 27.3 [26.0–27.7] 26.1 [24.9–26.4] 23.8 [22.8–24.2] 23.8 [23.7–24.2]
  C 24.8 [24.0–25.3] 16.3 [14.7–17.5] *** ### 13.8 [12.3–14.8] *** ###   
BE A 1.7 [−0.1–2.7] 2.9 [2.1–3.8] 2.5 [0.8–3.5] 0.2 [−0.9–2.2] −0.9 [−1.9–0.3]
(mmol/l) B 0.8 [0.5–3.1] 3.2 [1.6–3.7] 1.8 [0.5–2.2] 0.6 [−0.2–1.7] −0.9 [−0.9–0.3]
  C 0.3 [−0.5–1.0] −10.4 [−12.1–8.6] *** ### −13.5 [−15.6–12.2] *** ###   
pO2 A 169 [151–198] 431 [405–468] 413 [357–431] 417 [359–454] 415 [349–425]
(mmHg) B 156 [114–206] 399 [353–451] 387 [336–439] 367 [334–402] 349 [299–387]
  C 179 [147–208] 160 [115–213] *** ### 171 [126–239] *** ###   
pCO2 A 42 [39–45] 36 [33–36] 34 [32–36] 35 [33–36] 34 [32–36]
(mmHg) B 42 [40–48] 34 [33–37] 34 [32–35] 35 [33–36] 36 [32–38]
  C 42 [39–44] 43 [42–46] *** ### 42 [42–43] *** ###   
Hb A 13.7 [13.3–14.0] 7.9 [7.7–8.3] 7.8 [7.4–8.0] 7.6 [7.3–7.8] 7.3 [6.6–7.8]
(g/dl) B 13.7 [13.5–13.9] 8.5 [7.9–8.6] 8.0 [7.3–8.1] 7.8 [7.3–8.1] 7.6 [7.4–7.8]
  C 13.2 [12.9–13.6] 7.8 [7.6–8.1] 8.0 [7.6–8.2]   
Glu A 175 [165–180] 139 [133–141] 121 [119–128] 113 [103–119] 107 [101–114]
(mg/dl) B 179 [170–187] 142 [133–152] 124 [111–140] 124 [110–138] 118 [114–119] +  + 
  C 184 [166–194] 351 [311–363] *** ### 301 [274–310] *** ###   
Lac A 1.9 [1.8–2.2] 1.7 [1.5–1.9] 1.2 [1.0–1.4] 1.5 [1.2–1.6] 1.4 [1.4–1.5]
(mmol/l) B 1.8 [1.6–1.9] 1.7 [1.5–1.9] 1.3 [1.0–1.5] 1.6 [1.3–2.1] 1.7 [1.6–2.0] + 
  C 2.1 [1.9–2.3] 9.4 [9.0–9.9] *** ### 11.5 [10.8–13.2] *** ###   
  1. Animals were ventilated with inspiratory oxygen fraction of 0.5 (group A), 0.21 (group B) or 0 (group C). Blood was withdrawn for analysis at baseline and every 30 min after commencing the V-A ECMO. Animals of group C presented a lactate induced acidosis, as well as reduced pO2 and increased pCO2 levels. Data are shown as median (with 25th and 75th percentile). Asterisks, rhombus and crosses display the degree of statistical significance: A vs. C: *p < 0.05; ***p < 0.001; B vs. C: #p < 0.05; ##p < 0.01; ###p < 0.001; A vs B: +p < 0.05 ++p < 0.01
  2. Bic bicarbonate, BE base excess, pO2 arterial partial pressure of oxygen, pCO2 arterial partial pressure of carbone dioxide, Hb hemoglobin, Glu glucose, Lac lactate