Skip to main content

Table 2 Median CRP levels (Q1–Q3) in the LBA cohort in relation to CRP gene SNPs

From: CRP levels are significantly associated with CRP genotype and estrogen use in The Lifestyle, Biomarker and Atherosclerosis (LBA) study

 

Women total (n = 532)

Women estrogen users (n = 133)

Women non-estrogen users (n = 399)

Men total (n = 248)

CRP mg/L (n)

p

CRP mg/L (n)

p

CRP mg/L (n)

p

CRP mg/L (n)

p

Median

Q1–Q3

 

Median

Q1–Q3

 

Median

Q1–Q3

 

Median

Q1–Q3

 

rs2794521 (−717A>G)

            

 AA

0.75 (274)

0.36–1.90

0.622

2.22 (77)

0.74–3.38

0.187

0.62 (197)

0.28–1.14

0.894

0.54 (132)

0.27–1.23

0.484

 AG

0.67 (215)

0.31–1.63

 

1.22 (44)

0.65–3.16

 

0.55 (171)

0.29–1.19

 

0.52 (103)

0.22–1.05

 

 GG

0.61 (43)

0.35–1.40

 

0.90 (12)

0.58–2.20

 

0.55 (31)

0.30–0.91

 

0.63 (13)

0.38–1.32

 

rs3091244 (−286C>T>A)

            

 CC

0.55 (211)

0.28–1.06

< 0.001

0.75 (45)

0.48–2.00

< 0.001

0.49 (166)

0.26–0.95

0.032

0.44 (80)

0.22–1.26

0.325

 CA + CT

0.81 (253)

0.39.1.96

 

2.00 (64)

0.95–3.18

 

0.65 (189)

0.34–1.32

 

0.52 (122)

0.26–1.02

 

 AA + TA + TT

1.02 (68)

0.52–3.00

 

3.12 (24)

1.10–4.53

 

0.69 (44)

0.38–1.47

 

0.74 (46)

0.27–1.52

 

rs1800947 (+1059G>C)

            

 GG

0.75 (463)

0.37–1.94

< 0.001

1.77 (120)

0.76–3.24

0.064

0.61 (343)

0.31–1.28

0.002

0.56 (228)

0.26–1.24

0.029

 GC + CC

0.47 (69)

0.24–0.79

 

0.61 (13)

0.51–1.87

 

0.44 (56)

0.23–0.70

 

0.26 (20)

0.19–0.94

 

rs1130864 (+1444C>T)

            

 CC

0.59 (256)

0.29–1.18

< 0.001

0.87 (56)

0.53–2.24

< 0.001

0.52 (200)

0.26–0.99

0.076

0.46 (112)

0.22–1.26

0.515

 CT

0.84 (222)

0.38–2.14

 

2.30 (60)

1.04–3.59

 

0.65 (162)

0.34–1.29

 

0.57 (107)

0.28–10.2

 

 TT

1.02 (54)

0.48–2.91

 

2.89 (17)

1.04–4.37

 

0.75 (37)

0.36–1.50

 

0.54 (29)

0.25–1.64

 

rs1205 (+1846G>A)

            

 GG

0.85 (230)

0.42–2.33

< 0.001

2.27 (67)

0.92–4.23

0.011

0.64 (163)

0.34–1.40

0.006

0.56 (120)

0.25–1.26

0.260

 GA

0.67 (237)

0.32–1.48

 

1.36 (49)

0.58–2.52

 

0.56 (188)

0.29–1.16

 

0.57 (107)

0.24–1.05

 

 AA

0.47 (65)

0.23–1.04

 

0.67 (17)

0.51–2.39

 

0.36 (48)

0.21–0.89

 

0.32 (21)

0.18–1.40

 
  1. The p-values are based on Kruskal Wallis test (if three or more groups) or Mann–Whitney U test (if two groups)
Back to article page

BMC Cardiovascular Disorders

ISSN: 1471-2261

Contact us