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Table 2 CMR parameters compared between HFpEF and controls

From: Impact of different degrees of left ventricular strain on left atrial mechanics in heart failure with preserved ejection fraction

Parameters

HFpEF (n = 79)

Controls (n = 158)

p-value

Basic parameters

 LVEDV index (ml/m2)

66.6 ± 14.9

64.8 ± 12.1

0.315

 LVESV index (ml/m2)

21.3 ± 8.2

18.9 ± 6.3

0.013

 LVEF (%)

68.6 ± 7.6

71.5 ± 6.3

0.002

 LVMI (g/m2)

64.0 ± 19.7

53.2 ± 10.8

 < 0.001

 RVEDV index (ml/m2)

64.1 ± 16.8

65.6 ± 13.9

0.461

 RVEF (%)

57.5 ± 10.0

56.6 ± 8.5

0.467

LV strain parameters

 GLS (%)

 − 13.3 ± 3.4

 − 15.4 ± 2.2

 < 0.001

 GCS (%)

 − 16.4 ± 3.6

 − 18.9 ± 2.8

 < 0.001

 GRS (%)

28.1 ± 8.8

34.3 ± 8.1

 < 0.001

LA volume and mechanical parameters

 LAVimax (ml/m2)

45.1 ± 21.1

35.9 ± 10.3

 < 0.001

 LAVimin (ml/m2)

27.3 ± 20.9

16.7 ± 7.2

 < 0.001

 LAEF, total (%)

43.5 ± 16.8

54.2 ± 12.2

 < 0.001

 LAEF, passive (%)

20.8 ± 9.6

26.2 ± 9.5

 < 0.001

 LAEF, active (%)

25.5 ± 11.1

28.6 ± 9.1

0.043

 LA expansion index (%)

92.8 ± 57.2

132.0 ± 54.4

 < 0.001

 Conduit volume index (ml/m2)

27.5 ± 8.3

26.1 ± 9.3

0.236

 LASr (%)

19.5 ± 9.7

26.7 ± 8.8

 < 0.001

 LAScd (%)

 − 9.7 ± 5.9

 − 14.8 ± 7.4

 < 0.001

 LASct (%)

 − 10.7 ± 5.2

 − 12.4 ± 4.3

0.017

 Abnormal GLS (≥ − 16%)

59 (75.6%)

87 (56.1%)

0.004

 Abnormal LAVI (> 34 ml/m2)

54 (68.4%)

84 (53.5%)

0.029

 Abnormal LASr (< 23%)

49 (62.0%)

60 (38.5%)

0.001

 Abnormal LAEF (< 50%)

47 (59.5%)

43 (27.4%)

 < 0.001

 Heart rate (beats per minute)

73.0 ± 13.5

71.0 ± 12.6

0.237

  1. Data presented as mean ± standard deviation or number and percentage
  2. CMR indicates cardiac magnetic resonance; HFpEF heart failure with preserved ejection fraction; GCS global circumferential strain; GLS global longitudinal strain; GRS global radial strain; LAVimax maximal left atrial volume index; LAVimin minimal left atrial volume index; LAEF left atrial emptying fraction; LAScd left atrial strain during conduit phase; LASct left atrial strain during contraction phase; LASr left atrial strain during reservoir phase; LVEDV left ventricular end-diastolic volume; LVEF left ventricular ejection fraction; LVESV left ventricular end-systolic volume; LVMI LV mass index; RVEDV right ventricular end-diastolic volume; RVEF right ventricular ejection fraction
  3. A p-value < 0.05 indicates statistical significance (bold and italic)