Table 5 Left ventricular outcomes versus HbA1c Categories: Adjusted Model. Reference HbA1c < 5.7%)
Left Ventricular Measures | HbA1c 5.7–< 6.5% | HbA1c 6.5–< 8.0% | HbA1c ≥ 8.0% | n | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Mean difference | Percent parameter difference (95% CI) | Sig | Mean difference | Percent parameter difference (95% CI) | Sig | Mean difference | Percent parameter difference (95% CI) | Sig | ||
Left Ventricular Ejection Fraction (%) | 0.11 | 0.18 (− 1.00, 1.39) | 0.763 | − 1.34 | − 2.18 (− 4.55, 0.25) | 0.078 | − 0.20 | − 0.32 (− 2.69, 2.09) | 0.787 | 2082 |
Left Ventricular Fractional Shortening (%) | − 0.39 | − 1.02 (− 2.96, 0.97) | 0.314 | − 1.02 | − 2.64 (− 6.63, 1.50) | 0.208 | − 0.51 | − 1.34 (− 5.30, 2.79) | 0.519 | 1512 |
Left Ventricular End Diastolic Volume (ml/m2) | − 1.19 | − 2.25 (− 4.04, − 0.42) | 0.016 | − 1.45 | − 2.75 (− 6.40, 1.05) | 0.152 | − 2.11 | − 3.97 (− 7.47, − 0.34) | 0.032 | 2082 |
Left Ventricular End Systolic Volume (ml/m2) | − 0.40 | − 2.44 (− 5.53, 0.75) | 0.133 | − 0.20 | 1.25 (− 5.29, 8.23) | 0.716 | − 0.19 | − 1.15 (− 7.34, 5.46) | 0.726 | 2082 |
Stroke Volume Index (ml/m2) | − 0.75 | − 2.13 (− 4.07, − 0.14) | 0.036 | − 1.74 | − 4.84 (− 8.72, − 0.80) | 0.020 | − 2.09 | − 5.81 (− 9.53, − 1.93) | 0.004 | 2082 |
Cardiac Index (L/min/m2) | − 0.06 | − 2.28 (− 4.49, − 0.02) | 0.048 | 0.01 | 0.14 (− 4.49, 5.00) | 0.952 | 0.11 | 4.85 (0.15, 9.78) | 0.043 | 2082 |
Myocardial Contraction Fraction (%) | − 0.38 | − 0.72 (− 2.80, 1.41) | 0.507 | − 1.19 | − 2.21 (− 6.40, 2.15) | 0.315 | − 2.94 | − 5.38 (− 9.32, − 1.26) | 0.011 | 2082 |
Left Ventricular Mass Index (g/m2) | − 0.04 | − 0.06 (− 2.14, 2.06) | 0.953 | − 0.71 | − 1.01 (− 5.22, 3.39) | 0.647 | 1.42 | 2.06 (− 2.15, 6.46) | 0.341 | 2082 |
Relative Wall Thickness (cm) |  < 0.01 | 1.16 (− 0.53, 2.90) | 0.180 |  < 0.01 | 1.12 (− 2.36, 4.71) | 0.533 | 0.01 | 3.73 (0.26, 7.32) | 0.035 | 2082 |