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Table 5 Left ventricular outcomes versus HbA1c Categories: Adjusted Model. Reference HbA1c < 5.7%)

From: Glycemic status, non-traditional risk and left ventricular structure and function in the Jackson Heart Study

Left Ventricular Measures HbA1c 5.7–< 6.5% HbA1c 6.5–< 8.0% HbA1c ≥ 8.0% n
Mean difference Percent parameter difference (95% CI) Sig Mean difference Percent parameter difference (95% CI) Sig Mean difference Percent parameter difference (95% CI) Sig
Left Ventricular Ejection Fraction (%) 0.11 0.18 (− 1.00, 1.39) 0.763 − 1.34 − 2.18 (− 4.55, 0.25) 0.078 − 0.20 − 0.32 (− 2.69, 2.09) 0.787 2082
Left Ventricular Fractional Shortening (%) − 0.39 − 1.02 (− 2.96, 0.97) 0.314 − 1.02 − 2.64 (− 6.63, 1.50) 0.208 − 0.51 − 1.34 (− 5.30, 2.79) 0.519 1512
Left Ventricular End Diastolic Volume (ml/m2) − 1.19 − 2.25 (− 4.04, − 0.42) 0.016 − 1.45 − 2.75 (− 6.40, 1.05) 0.152 − 2.11 − 3.97 (− 7.47, − 0.34) 0.032 2082
Left Ventricular End Systolic Volume (ml/m2) − 0.40 − 2.44 (− 5.53, 0.75) 0.133 − 0.20 1.25 (− 5.29, 8.23) 0.716 − 0.19 − 1.15 (− 7.34, 5.46) 0.726 2082
Stroke Volume Index (ml/m2) − 0.75 − 2.13 (− 4.07, − 0.14) 0.036 − 1.74 − 4.84 (− 8.72, − 0.80) 0.020 − 2.09 − 5.81 (− 9.53, − 1.93) 0.004 2082
Cardiac Index (L/min/m2) − 0.06 − 2.28 (− 4.49, − 0.02) 0.048 0.01 0.14 (− 4.49, 5.00) 0.952 0.11 4.85 (0.15, 9.78) 0.043 2082
Myocardial Contraction Fraction (%) − 0.38 − 0.72 (− 2.80, 1.41) 0.507 − 1.19 − 2.21 (− 6.40, 2.15) 0.315 − 2.94 − 5.38 (− 9.32, − 1.26) 0.011 2082
Left Ventricular Mass Index (g/m2) − 0.04 − 0.06 (− 2.14, 2.06) 0.953 − 0.71 − 1.01 (− 5.22, 3.39) 0.647 1.42 2.06 (− 2.15, 6.46) 0.341 2082
Relative Wall Thickness (cm)  < 0.01 1.16 (− 0.53, 2.90) 0.180  < 0.01 1.12 (− 2.36, 4.71) 0.533 0.01 3.73 (0.26, 7.32) 0.035 2082
  1. Each row represents a separate model for Left ventricular outcomes and were adjusted for diabetes duration, Hypertension age, gender, physical activity, highest level of education, nutrition pattern, dyslipidemia smoking status, alcohol use, use of crack or cocaine, carvedilol dose equivalent, calcium channel blockers, diuretics, Angiotensin converting enzyme inhibitor, Angiotensin Receptor Blocker. Only LVEF, LV FS, MCF and RWT which were additionally controlled for log of BMI