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Table 3 Multivariate logistic regression to examine the association between blood pressure groups and diagnosis of cerebrovascular disease, transient ischemic attack and stroke stratified by age, smoking status, hypertension, use of antihypertensive medications, obesity and peripheral vascular disease

From: Prevalence of orthostatic hypertension and its association with cerebrovascular diagnoses in patients with suspected TIA and minor stroke

Outcomes/level of adjustment

Rise in systolic BP compared to no rise

Rise in diastolic BP compared to no rise

Rise in both systolic and diastolic BP compared to no rise

n

OR (95% CI)

n

OR (95% CI)

n

OR (95% CI)

Odds of CVD

      

 Age ≤ 65 years

828

0.73 (0.40–1.31)

828

0.73 (0.53–1.00)

828

0.47 (0.21–1.03)

 Age > 65 years

2275

0.85 (0.57–1.27)

2275

0.90 (0.73–1.11)

2275

0.69 (0.38–1.24)

 Non-smoker

1255

0.87 (0.51–1.51)

1255

0.80 (0.61–1.05)

1255

0.34 (0.15–0.80)

 Smoker

1848

0.77 (0.51–1.16)

1848

0.93 (0.74–1.15)

1848

0.73 (0.41–1.29)

 No hypertension

1070

0.68 (0.39–1.18)

1070

0.88 (0.66–1.16)

1070

0.42 (0.19–0.92)

 Hypertension

2033

0.84 (0.55–1.28)

2033

0.88 (0.70–1.09)

2033

0.64 (0.36–1.15)

 No antihypertensive

1260

0.70 (0.43–1.16)

1260

0.85 (0.65–1.09)

1260

0.48 (0.24–0.98)

 Antihypertensive

1843

0.85 (0.55–1.33)

1843

0.91 (0.72–1.14)

1843

0.63 (0.34–1.17)

 No obesity

2303

0.87 (0.58–1.30)

2303

0.90 (0.74–1.10)

2303

0.74 (0.42–1.28)

 Obesity

800

0.67 (0.37–1.22)

800

0.87 (0.62–1.22)

800

0.31 (0.12–0.80)

 No PVD

2991

0.79 (0.57–1.11)

2991

0.89 (0.75–1.06)

2991

0.58 (0.36–0.92)

 PVD

112

0.35 (0.04–2.81)

112

0.71 (0.25–2.05)

112

1 (no events)

 Odds of stroke

      

Age ≤ 65 years

828

1.42 (0.70–2.89)

828

0.71 (0.46–1.12)

828

1.30 (0.54–3.13)

 Age > 65 years

2275

0.65 (0.38–1.10)

2275

1.23 (0.97–1.55)

2275

0.71 (0.33–1.53)

 Non-smoker

1255

0.56 (0.25–1.25)

1255

1.03 (0.73–1.44)

1255

0.46 (0.14–1.55)

 Smoker

1848

1.01 (0.61–1.66)

1848

1.15 (0.89–1.50)

1848

1.17 (0.60–2.27)

 No hypertension

1070

0.68 (0.31–1.49)

1070

1.08 (0.74–1.56)

1070

0.92 (0.34–2.46)

 Hypertension

2033

0.87 (0.52–1.44)

2033

1.11 (0.87–1.43)

2033

0.86 (0.42–1.74)

 No antihypertensive

1260

0.85 (0.43–1.65)

1260

1.11 (0.80–1.55)

1260

1.10 (0.47–2.58)

 Antihypertensive

1843

0.80 (0.46–1.37)

1843

1.10 (0.84–1.43)

1843

0.75 (0.34–1.63)

 No obesity

2303

0.86 (0.52–1.42)

2303

1.10 (0.87–1.40)

2303

1.10 (0.57–2.13)

 Obesity

800

0.83 (0.38–1.84)

800

1.12 (0.74–1.71)

800

0.60 (0.17–2.06)

 No PVD

2991

0.82 (0.54–1.26)

2991

1.13 (0.92–1.40)

2991

0.91 (0.51–1.61)

 PVD

112

0.91 (0.04–20.00)

112

0.32 (0.06–1.77)

112

1 (no events)

 Odds of TIA

      

 Age ≤ 65 years

828

0.46 (0.21–1.01)

828

0.84 (0.59–1.19)

828

0.17 (0.04–0.73)

 Age > 65 years

2275

1.12 (0.75–1.68)

2275

0.77 (0.62–0.95)

2275

0.86 (0.46–1.60)

 Non-smoker

1255

1.22 (0.69–2.14)

1255

0.77 (0.57–1.03)

1255

0.45 (0.17–1.20)

 Smoker

1848

0.74 (0.47–1.15)

1848

0.83 (0.66–1.04)

1848

0.60 (0.32–1.15)

 No hypertension

1070

0.80 (0.45–1.43)

1070

0.83 (0.61–1.12)

1070

0.34 (0.13–0.91)

 Hypertension

2033

0.92 (0.59–1.42)

2033

0.80 (0.64–1.00)

2033

0.67 (0.35–1.29)

 No antihypertensive

1260

0.73 (0.43–1.26)

1260

0.78 (0.59–1.02)

1260

0.35 (0.14–0.86)

 Antihypertensive

1843

1.00 (0.63–1.58)

1843

0.84 (0.66–1.06)

1843

0.73 (0.37–1.45)

 No obesity

2303

0.95 (0.63–1.44)

2303

0.83 (0.68–1.03)

2303

0.65 (0.35–1.20)

 Obesity

800

0.69 (0.35–1.36)

800

0.79 (0.55–1.15)

800

0.29 (0.08–0.99)

 No PVD

2991

0.88 (0.62–1.26)

2991

0.81 (0.67–0.97)

2991

0.56 (0.32–0.95)

 PVD

112

0.34 (0.04–2.84)

112

1.30 (0.43–3.89)

112

1 (no events)

  1. Adjusted for age, sex, smoking, alcohol consumption, body mass index, previous stroke, transient ischemic attack, atrial fibrillation, hypertension, ischemic heart disease, peripheral vascular disease, diabetes, hyperlipidemia, use of thiazide, ACE inhibitor or ARB, beta-blocker, diuretic, calcium channel blocker and alpha blocker. Note that for analysis of a particular variable group, the adjustments were made for all variables except for the particular variable
  2. CVD cerebrovascular disease (stroke or TIA), PVD peripheral vascular disease, TIA transient ischemic attack