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Table 3 Univariate and multivariate logistic regression analyses of 30-day favorable neurological outcomes and 30-day survival after cardiac arrest

From: Association between short-term neurological outcomes and extreme hyperoxia in patients with out-of-hospital cardiac arrest who underwent extracorporeal cardiopulmonary resuscitation: a retrospective observational study from a multicenter registry

 

Crude OR (95% CI)

p value

Adjusted OR (95% CI)

p value

For 30-day favorable neurological outcomes

Normoxia

Reference

 

Reference

 

Moderate hyperoxia

0.92 (0.61–1.39)

0.69

0.86 (0.55–1.35)

0.51

Extreme hyperoxia

0.53 (0.32–0.86)

0.010

0.48 (0.29–0.82)

0.007

For 30-day survival

Normoxia

Reference

 

Reference

 

Moderate hyperoxia

0.90 (0.65–1.27)

0.56

0.92 (0.63–1.34)

0.66

Extreme hyperoxia

0.64 (0.45–0.93)

0.018

0.66 (0.44–1.00)

0.048

  1. Multiple propensity scores were calculated by adjusting for the following factors: age, sex, witness, bystander cardiopulmonary resuscitation, initial cardiac rhythm, pre-hospital shock delivery, pre-hospital adrenaline administration, pre-hospital advanced airway management, time from call to scene, time from scene to hospital arrival, etiology, cardiac rhythm on arrival, transient return of spontaneous circulation before ECMO pump-on, time from hospital arrival to ECMO pump-on, and time from hospital arrival to blood gas analysis. Adjusted ORs were calculated, controlling for the multiple propensity scores and the following variables: PaCO2, HCO3− concentration, lactate level, intra-aortic balloon pump use, percutaneous coronary intervention, and targeted temperature management
  2. CI confidence interval, ECMO extracorporeal membrane oxygenation, HCO3− bicarbonate ion, OR odds ratio, PaCO2 partial pressure of arterial carbon dioxide, PaO2partial pressure of arterial oxygen