The effect of subdiaphragmatic vagotomy on heart rate variability and lung inflammation in rats with severe hemorrhagic shock

Table 1 Comparison of baseline and end arterial blood gas parameters, and end values of lactate in the experimental groups

	Sham	Vag	SHS	Vag + SHS
Start of experiment
pH	7.47 ± 0.00	7.46 ± 0.03	7.43 ± 0.00	7.45 ± 0.01
PaCO₂ (mmHg)	30.67 ± 0.77	32.56 ± 1.14	34.55 ± 0.83	34.94 ± 0.95
PaO₂ (mmHg)	63.75 ± 1.37	71.50 ± 4.50	65.00 ± 1.73	67.16 ± 3.29
HCO3^−a (mmol/L)	22.60 ± 0.71	23.06 ± 1.01	24.31 ± 0.35	25.13 ± 0.34
BE	− 0.32 ± 0.61	− 0.23 ± 1.32	0.58 ± 0.22	1.12 ± 0.60
End of experiment
pH	7.48 ± 0.00	7.48 ± 0.01	7.36 ± 0.02 ^#	7.29 ± 0.02 ^a
PaCO₂ (mmHg)	29.15 ± 0.86	29.75 ± 1.08	23.52 ± 1.29	24.92 ± 1.05
PaO₂ (mmHg)	63.50 ± 0.95	67.66 ± 0.88	62.57 ± 0.86	75.28 ± 2.35 ^b
HCO₃⁻ (mmol/L)	21.87 ± 0.98	22.73 ± 0.56	14.5 ± 0.54 ^#	12.55 ± 0.64 ^a
BE	− 0.60 ± 0.94	− 0.17 ± 0.45	− 9.5 ± 0.85 ^#	− 12.3 ± 1.01 ^a
Lactate (mmol/dL)	13.65 ± 2.23	12.1 2 ± 2.64	65.16 ± 9.53 ^#	89.98 ± 7.44 ^a

Data are mean ± SE in the Sham (N = 5), Vag (N = 5), SHS (N = 7), and Vag + SHS (N = 8) groups. The comparison between groups was performed by analysis of variance ANOVA and unpaired student t-test. ^#P < 0.05, versus the Sham group; ^aP < 0.05, versus the Vag group; ^bP < 0.05, versus the SHS group

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