From: Long noncoding RNA MALAT1 polymorphism predicts MACCEs in patients with myocardial infarction
 | Total (n = 1224) | Controls (n = 729) | MI patients (n = 495) | ||||||
---|---|---|---|---|---|---|---|---|---|
nonMACCE (n = 1050) | MACCE (n = 174) | P value | nonMACCE (n = 678) | MACCE (n = 51) | P value | nonMACCE (n = 372) | MACCE (n = 123) | P value | |
Male, n (%) | 641 (61.1%) | 118 (67.9%) | 0.434 | 334 (49.3%) | 18 (35.3%) | 0.288 | 307 (82.5%) | 100 (81.3%) | 0.938 |
Age (years) | 55.05 ± 10.92 | 60.86 ± 11.82 | < 0.001 | 54.53 ± 9.96 | 59.76 ± 9.80 | 0.006 | 56.53 ± 12.38 | 63.01 ± 12.47 | < 0.001 |
BMI (kg/m2) | 25.83 ± 3.56 | 25.54 ± 3.30 | 0.419 | 26.25 ± 3.91 | 25.88 ± 3.51 | 0.703 | 25.63 ± 3.26 | 25.29 ± 3.25 | 0.488 |
Hypertension, n (%) | 450 (42.9%) | 88 (50.6%) | 0.246 | 300 (44.3%) | 24 (47.1%) | 0.796 | 105 (28.2%) | 64 (52.0%) | 0.002 |
Smoker, n (%) | 411 (39.1%) | 65 (37.4%) | 0.816 | 195 (28.8%) | 10 (19.6%) | 0.338 | 216 (58.1%) | 55 (44.7%) | 0.180 |
Drinker, n (%) | 324 (30.9%) | 47 (27.0%) | 0.493 | 172 (25.4%) | 8 (15.7%) | 0.241 | 152 (40.9%) | 39 (31.7%) | 0.231 |
Diabetes, n (%) | 156 (14.9%) | 42 (24.1%) | 0.014 | 72 (10.6%) | 8 (15.7%) | 0.361 | 84 (22.6%) | 34 (27.6%) | 0.411 |
Glucose (mmol/L) | 5.45 (4.71, 7.47) | 7.16 (5.27, 9.36) | < 0.001 | 4.94 (4.53, 5.64) | 4.76 (4.29, 5.29) | 0.086 | 7.58 (6.35, 10.30) | 8.01 (6.74, 10.58) | 0.027 |
TG (mmol/L) | 1.55 (1.05, 2.25) | 4.28 (3.56, 5.04) | 0.014 | 1.51 (1.02, 2.13) | 1.25 (0.955, 1.705) | 0.139 | 1.60 (1.08, 2.48) | 1.42 (0.865, 2.10) | 0.189 |
TC (mmol/L) | 4.34 ± 1.07 | 4.37 ± 1.21 | 0.909 | 4.24 ± 0.94 | 4.07 ± 0.91 | 0.355 | 4.66 ± 1.18 | 4.71 ± 1.37 | 0.785 |
HDL-C (mmol/L) | 1.08 ± 0.29 | 1.02 ± 0.27 | 0.014 | 1.12 ± 0.32 | 1.12 ± 0.28 | 0.992 | 1.04 ± 0.23 | 1.00 ± 0.24 | 0.257 |
LDL-C (mmol/L) | 2.79 ± 0.86 | 2.86 ± 0.98 | 0.331 | 2.69 ± 0.8 | 2.59 ± 0.74 | 0.494 | 3.02 ± 0.89 | 3.04 ± 1.18 | 0.895 |
ApoA (mmol/L) | 1.22 ± 0.31 | 1.16 ± 0.27 | 0.018 | 1.23 ± 0.26 | 1.13 ± 0.24 | 0.032 | 1.20 ± 0.44 | 1.19 ± 0.29 | 0.795 |
ApoB (mmol/L) | 0.87 ± 0.30 | 0.88 ± 0.33 | 0.792 | 0.85 ± 0.25 | 0.82 ± 0.26 | 0.469 | 0.94 ± 0.40 | 0.94 ± 0.41 | 0.987 |
Lp (a) (mmol/L) | 144.80 (88.13, 253.53) | 157.99 (99.41, 265.90) | 0.622 | 137.79 (86.61, 232.21) | 137.48 (97.28, 224.08) | 0.961 | 165.00 (91.51, 278.47) | 176.68 (105.91, 301.97) | 0.763 |
SBP (mmHg) | 123.43 ± 17.08 | 122.84 ± 20.03 | 0.715 | 125.39 ± 16.39 | 124.12 ± 19.62 | 0.666 | 118.93 ± 16.77 | 121.54 ± 20.66 | 0.260 |
DBP (mmHg) | 122.84 ± 20.03 | 76.29 ± 11.78 | 0.292 | 76.71 ± 11.02 | 75.74 ± 13.70 | 0.663 | 75.26 ± 12.55 | 73.85 ± 13.24 | 0.398 |