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Table 1 Epidemiologic and clinic chracteristics of the population according to the sex and the management sector

From: Epidemiologic features and management of hypertension in Tunisia, the results from the Hypertension National Registry (NaTuRe HTN)

 

All population

Female

Male

p (male vs female)

Public

Private

p (public vs private)

N

25,890

14,166

11,700

 

20,192

5698

 

Age (years)

       

Median (min–max)

Mean ± SD

64.00 (18–118)

64.4 ± 12.2

64 (18–118)

64.5 ± 12.2

64 (18–108)

64.2 ± 12.2

0.059*

64 (18–118)

64.46 ± 12.2

65 (18–101)

64.19 ± 12.1

0.4

Age > 65 yo (%)

12,662 (49.3)

6982 (49.7)

5673 (48.8)

0.1

9860 (49.1)

2802 (50.1)

0.4

Ramadan Inclusion (%)

16,565 (64)

9155 (64.6)

7403 (63.3)

0.02

13,173 (35.2)

3392 (59.5)

 < 10–3

Education level

       

Illiterate (%)

Primary school (%)

Secondary school (%)

University school (%)

Unspecified (%)

5527 (21.3)

5475 (21.1)

4493 (17.4)

2428 (9.4)

7967 (30.8)

4261 (30.1)

3124 (22.1)

1880 (13.3)

825 (5.8)

4076 (28.8)

1262 (10.8)

2346 (20.1)

2612 (22.3)

1600 (13.7)

3880 (33.2)

< 10–3

4527 (22.4)

4384 (21.7)

3139 (15.5)

1439 (7.1)

6703 (33.2)

1000 (17.6)

1091 (19.1)

1354 (23.8)

989 (17.4)

1264 (22.2)

 < 10–3

Health insurance coverage

       

Private insurance (%)

National insurance (%)

State Medicare (%)

None insurance (%)

Unspecified (%)

762 (2.9)

18,453 (71.3)

5052 (19.5)

790 (3.1)

833 (3.2)

399 (2.8)

9806 (69.2)

3114 (22)

408 (2.9)

439 (3.1)

363 (3.1)

8632 (73.8)

1936 (16.5)

382 (3.3)

387 (3.3)

< 10–3

434 (2.1)

14,165 (70.2)

4724 (23.4)

520 (2.6)

346 (1.7)

328 (5.8)

4285 (75.2)

328 (5.8)

270 (4.7)

487 (8.5)

 < 10–3

Smoking (%)

3630 (14)

391 (2.8)

3236 (27.7)

 < 10–3

3021 (15)

609 (10.7)

 < 10–3

Diabetes (%)

10,204 (39.4)

5621 (39.7)

4583 (39.2)

0.4

8185 (40.5)

2029 (35.6)

 < 10–3

Obesity (%)

6979 (25.8)

4927 (34.7)

2065 (17.6)

 < 10–3

5207 ( 25.9)

2590 (46.3)

 < 10–3

Corpulence

       

Overweight (%)

Moderate obesity (%)

morbid Obesity (%)

severe Obesity (%)

11,539 (44.6)

5182 (20)

461 (1.8)

1354 (5.2)

5984 (42.2)

3509 (24.8)

375 (2.6)

1043 (7.4)

5546 (47.4)

1671 (14.3)

85 (0.7)

310 (2.6)

 < 10–3

9454 (46.8)

3946 (19.5)

302 (1.5)

959 (4.7)

2085 (36.6)

1236 (21.7)

959 (2.8)

395 (6.9)

 < 10–3

BMI (kg/cm2)

       

Median (min–max)

Mean ± SD

27.5 (13.7–72.2)

28.1 ± 4.57

28.3 (14–70)

29.01 ± 4.57

27.07 ± 3.93

 < 10–3*

27.3 (14–72)

27.9 ± 4.3

29 (13.7–66.9)

29.08 ± 5.13

 < 10–3*

Newly diagnosed HTN (%)

1475 (5.7)

705 (5.1)

770 (6.8)

 < 10–3

953 (4.7)

522 (9.2)

 < 10–3

Moderate Renal Failure (%)

1524 (5.9)

672 (4.7)

851 (7.3)

 < 10–3

1305 (6.5)

219 (3.8)

 < 10–3

Hypothyroidism (%)

1384 (5.3)

1136 (8)

248 (2.1)

 < 10–3

1034 (5.1)

350 (6.1)

0.002

Apnea syndrome

Confirmed (%)

Suspected (%)

469 (1.8)

843 (3.3)

257 (1.8)

499 (3.5)

211 (1.8)

343 (2.9)

0.02

276 (1.4)

505 (2.5)

193 (3.4)

338 (5.9)

 < 10–3

COPD (%)

519 (2)

137 (1)

382 (3.3)

 < 10–3

380 (1.9)

139 (2.4)

0.008

Stroke history (%)

1707 (6.6)

796 (5.6)

910 (7.8)

 < 10–3

1311 (6.5)

396 (6.9)

0.2

Coronary disease (%)

4797 (18.5)

1742 (12.3)

3048 (26.1)

 < 10–3

3941 (19.8)

856 (15)

 < 10–3

SBP (mmHg)

       

Median ( min–max)

Mean ± SD

135 (80–260)

138.8 ± 19.6

135 (80–260)

138.5 ± 19.7

140 (85–250)

139.2 ± 19.4

 < 10–3*

140 (80–260)

138.9 ± 19.7

134.5 (80–260)

138.6 ± 19

0.1*

DBP (mmHg)

       

Median ( min–max)

Mean ± SD

80 (40–140)

79.03 ± 11.1

80 (40–140)

78.8 ± 10.9

80 (40–140)

79.3 ± 11.3

0.005*

80 (40–140)

78.9 ± 11.2

80 (40–140)

79.4 ± 10.7

0.6*

HTN History > 6 months

23,601 (91.1)

13,058 (55.3)

10,543 (44.7)

 < 10–3

18,613 (95.1)

4988 (90.5)

 < 10–3

Controlled HTN

(Target < 140/90 mmHg) (%)

12,206 (51.7)

6825 (52.4)

5371 (50.9)

0.032

9361 (50.3)

2845 (57)

 < 10–3

Controlled HTN (Target < 130/80 mmHg) (%)

4386 (18.6%)

2486 (19.1)

1896 (18)

0.033

3357 (18)

1029 (20.6)

 < 10–3

Heart rate (bpm)

Median ( min–max)

Mean ± SD

74 (40–150)

73.8 ± 11

74 (40–150)

74.1 ± 11.1

73 (40–150)

73.5 ± 10.9

 < 10–3*

74 (40–150)

74.3 ± 10.8

70 (40–150)

72.2 ± 11.8

 < 10–3

Heart rate > 80 bpm (%)

4878 (19.2)

2754 (19.8)

2120 (18.5)

0.009

3895 (19.6)

983 (17.8)

0.003

LVH on EKG or TTE (%)

3377 (13)

1399 (9.9)

1482 (12.7)

 < 10–3

2125 (10.5)

758 (13.3)

 < 10–3

Atrial fibrillation (%)

1914 (7.4)

1130 (8)

783 (6.7)

 < 10–3

1527 (7.6)

387 (6.8)

0.05

Recent lab tests < 6 months

14,737 (56.9)

8202 (57.9)

6521 (55.7)

 < 10–3

10,302 (77.8)

4435 (51)

 < 10–3

Fasting Glucose (g/l)

       

Median ( min–max)

Mean ± SD

1.1 (0.5–3.9)

1.3 ± 0.5

1.15 (0.6–3.97)

1.8 ± 6.1

1.1 (0.6–3.9)

1.6 ± 3.7

0.8*

1.129 (0.6–3.9)

1.6 ± 2.5

1.1 (0.6–3.8)

1.9 ± 7.6

 < 10–3*

Creatinine (µmol/l)

       

Median ( min–max)

Mean ± SD)

81 (30–700)

92.6 ± 50.7

76 (30–681)

85 ± 45.5

89 (32–700)

102 ± 55.11

 < 10–3*

80 (30–700)

93.1 ± 53.7

85 (30–663)

90.5 ± 38.5

 < 10–3*

Creatinine clearance (ml/min)

       

Median (min–max)

Mean ± SD

88.4 (7–287)

90.4 ± 33.5

96.4 (7.62–287.3)

98.5 ± 35.3

79.7 (7.3–246)

80.3 ± 28

< 10–3*

89.2 (7.3–287)

91 ± 34.6

85 (7.8–262)

88 ± 29

 < 10–3*

Total Cholesterol (g/l)

       

Median (min–max)

Mean ± SD

1.8 (1–5)

1.9 ± 0.6

1.8 (1–5)

1.96 ± 0.6

1.7 (1–5)

1.84 ± 0.6

 < 10–3*

1.8 (1–5)

1.8 ± 0.4

1.8 (1–5)

1.9 ± 0.7

0.6*

K+ (mmol/l)

       

Median (min–max)

Mean ± SD

4.1 (2.4–7)

4.1 ± 0.4

4.1 (2.5–6.8)

4.15 ± 0.4

4.1 (2.4–7)

4.1 ± 0.4

 < 10–3*

4.1 (2.45–7)

4.1 ± 0.48

4.1 (2.5–6.8)

4.1 ± 0.42

0.005

Microalbuminuria test during the last year (%)

4042 (15.6)

2226 (15.7)

1814 (15.5)

0.6

2190 (10.8)

1852 (32.5)

 < 10–3

Positive Microalbuminuria (% among people who got the test)

1365 (33.8)

652 (29.3)

713 (39.3)

 < 10–3*

910 (41.6)

455 (24.61)

 < 10–3

Drug treatment

       

No drug (%)

Monotherapy (%)

Biotherapy (%)

tritherapy or more (%)

4037 (15.6)

12,042 (46.5)

6614 (25.5)

3197 (12.3)

2170 (15.3)

6626 (46.8)

3646 (25.7)

1724 (12.2)

1862 (15.9)

5408 (46.2)

2961 (25.3)

1469 (12.6)

0.3

3032 (15)

9794 (48.5)

5032 (24.9)

2334 (11.6)

1005 (17.6)

2248 (39.5)

1582 (27.8)

863 (15.1)

 < 10–3

Antihypertensive drugs

       

ACE (%)

11,770 (45.5)

6420 (45.3)

5341 (45.6)

0.5

9251 (45.8)

2519 (44.2)

0.03

ARB (%)

5587 (20.6)

3012 (21.3)

2569 (22)

0.17

3156 (15.6)

2431 (42.7)

 < 10–3

CCB (%)

8028 (31.0)

4392 (31)

3630 (31)

0.9

6306 (31.2)

1722 (30.2)

0.14

Diuretics (%)

5514 (21.3)

3061 (21.6)

2446 (20.9)

0.17

4304 (21.3)

1210 (21.2)

0.8

Betablockers (%)

5734 (22.1)

3172 (22.4)

2554 (21.8)

0.27

4445 (22)

1289 (22.6)

0.3

Salt restriction (%)

13,891 (53.7)

7837 (55.3)

6043 (51.6)

 < 10–3

10,789 (53.4)

3102 (54.4)

0.1

ABPM (%)

656 (2.5)

352 (2.5)

304 (2.6)

0.5

314 (1.6)

342 (6)

 < 10–3

SMBP (%)

1630 (6.3)

868 (6.1)

762 (6.5)

0.2

1053 (4.1)

577 (10.1)

 < 10–3

Drug compliance (%)

19,539 (75.5)

10,874 (76.8)

8651 (73.9)

 < 10–3

15,326 (75.9)

4213 (73.9)

0.002

Physical activity (%)

3845 (14.9)

1598 (11.3)

2243 (19.2)

 < 10–3

2748 (13.6)

1097 (19.3)

 < 10–3

  1. *Mann–Whitney nonparametric test
  2. ABPM: Ambulatory blood pressure monitoring, ACE: Antagonist of conversion enzyme, ARB: Angiotensin Receptor Blockers, BMI: Body mass Index, CCB: Calcium Channels Blockers, COPD: Chronic obstructive pulmonary disease, DBP: Diastolic Blood Pressure, EKG: electrocardiogram, HTN: hypertension, LVH: Left Ventricle Hypertrophy, SD: Standard Deviation, SBP: systolic Blood Pressure, SMBP: Self measured Blood Pressure, TTE: Transthoracic echocardiography, yo: year-old